We have collected information about Targeting Tumors With Non Viral Gene Delivery Systems for you. Follow the links to find out details on Targeting Tumors With Non Viral Gene Delivery Systems.
https://www.sciencedirect.com/science/article/pii/S1359644602022432
Targeting therapeutic genes to tumors is an attractive concept in curing malignant diseases. Systemic gene delivery systems are needed for therapeutic applications in which the target cells are not directly accessible, and which can only be reached via the systemic route.Author: Manfred Ogris, Ernst Wagner
https://www.researchgate.net/publication/11403194_Targeting_tumors_with_non-viral_gene_delivery_systems
Targeting therapeutic genes to tumors is an attractive concept in curing malignant diseases. Systemic gene delivery systems are needed for therapeutic applications in which the target cells are ...
https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
Gene delivery systems include viral vectors and non-viral vectors. Viral vectors are the most effective, but their application is limited by their immunogenicity, oncogenicity and the small size of the DNA they can transport. Non-viral vectors are safer, of low cost, more reproducible and do not present DNA size limit.Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · INTRODUCTION. Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[] Different types of gene delivery systems may be applied in gene therapy to restore a specific gene function or turning off a special gene(s).
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/gene-delivery-systems-recent-progress-in-viral-and-non-viral-therapy
Current gene delivery systems are divided into three categories: viral-based, non-viral based, and combined hybrid systems. Viral gene delivery systems consist of viruses that are modified to be replication-deficient which can deliver genes to the target cells to provide expression.Author: Erdal Cevher, Ali Demir Sezer, Emre Şefik Çağlar
https://onlinelibrary.wiley.com/doi/full/10.1002/jgm.3092
Apr 16, 2019 · In cancer immunotherapy, NP‐mediated gene delivery systems can efficiently boost the immune response and attenuate immunosuppression. 32, 33 The encapsulation of a gene/cargo into non‐viral gene delivery systems (polymeric or lipid NPs) is emerging as a promising strategy that can target tumor cells, dendritic cells (DCs) and T lymphocytes.Author: Weiqi Wang, Weiqi Wang, Madiha Saeed, Yao Zhou, Lili Yang, Dangge Wang, Haijun Yu
https://www.researchgate.net/publication/253648700_Delivery_systems_for_gene_therapy
Delivery systems for gene therapy. ... Viral and non-viral gene delivery vehicles, commonly referred to as vectors, are modified to enhance delivery efficiency to target locations in the CNS ...Author: Shrikant Mali
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jgm.3092
vectors and thus comprise a promising gene delivery strategy in the clinic. In cancer immunotherapy, NP‐mediated gene delivery systems can efficiently boost the immune response and attenuate immunosuppression.32,33 The encapsulation of a gene/cargo into non‐viral gene delivery systems (polymeric or lipid NPs) isAuthor: Weiqi Wang, Weiqi Wang, Madiha Saeed, Yao Zhou, Lili Yang, Dangge Wang, Haijun Yu
https://www.sciencedirect.com/science/article/pii/S0168365915302649
A list of non-viral gene therapy systems used in clinical trials. (Data obtained and compiled from www.clinicaltrials.gov.) Note: Most of these leading technologies are still injectables; the proportion of non-invasive administration methods reflects the progress.Author: Marianna Foldvari, Ding Wen Chen, Nafiseh Nafissi, Daniella Calderon, Lokesh Narsineni, Amirreza Raf...
http://nmj.mums.ac.ir/article_12334.html
On the other hand, non-viral vectors have less toxicity and immunogenic response and are easier to prepare. For a successful gene therapy, the cargo must be delivered to the target site. However, various barriers are faced by non-viral vectors, which make the gene delivery to the target site difficult.Author: Faisal Qaisar, Anum Habib, Maira Riaz, Zia Ur Rehman
Searching for Targeting Tumors With Non Viral Gene Delivery Systems?
You can just click the links above. The data is collected for you.
