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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/targeted-drug-delivery
“Active” targeting often wrongly evokes the idea of a targeting moiety propelling a delivery system to a site of action; instead, targeted systems rely on bodily distribution networks (blood circulation, diffusion, interstitial fluid movements, etc.) for proximal delivery to a specific site, where the targeting moiety then interacts with its partner (ligand-receptor or receptor-ligand) to promote site-specific retention and …
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Enhancing Targeted Intracellular Delivery Just as the immune system defends the body against disease, each cell also has internal processes to recognize and get rid of potentially harmful substances and foreign objects. These foreign agents may include drugs enclosed in targeted delivery vehicles.
https://www.slideshare.net/anushanagraj/targeted-drug-delivery-system
Sep 11, 2014 · STRATEGIES OF DRUG TARGETING 1) Passive Targeting : • Drug delivery systems which are targeted to systemic circulation are characterized as Passive delivery systems. • In this technique drug targeting occurs because of the body’s natural response to physicochemical characteristics of the drug or drug carrier system.
https://accesspharmacy.mhmedical.com/content.aspx?bookid=1592§ionid=100674326
Discuss why biologic drugs may require delivery and/or targeting systems. Describe the main methods used to deliver and target biologic drugs and give examples. Explain the difference between active and passive targeting. State whether generic biologics exist, and if not, describe why.
https://www.academia.edu/9239676/TARGETED_DRUG_DELIVERY_SYSTEM
TARGETED DRUG DELIVERY SYSTEM
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.0c00014
On the one hand, CAF-targeted nano delivery systems inhibit the pro-tumor signaling pathway between CAFs and cancer cells to reverse tumorigenesis, immunosuppression or drug resistance in the tumor microenvironment, thus improving the sensitivity to anti-tumor treatments.Author: Jian Guo, Huating Zeng, Yan Chen
http://ijpsr.com/bft-article/novel-drug-delivery-systems-an-overview/?view=fulltext
New drug delivery systems have been developed or are being developed to overcome the limitation of the conventional drug delivery systems to meet the need of the healthcare profession. These systems can be characterised as controlled drug release systems and targeted drug delivery systems. The therapeutic benefits of these new systems include:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · As most of the current delivery systems need no effective targeting, the way is proper. The system has been utilized in the delivery of CFTR gene by lipid and adenoviral vectors to a specific site in the respiratory tract and is also used in the treatment of different cancers.
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