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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Once accumulated at the target site, hydrophobic biodegradable polymeric nanoparticles can act as a local drug depot depending on the make-up of the carrier, providing a source for a continuous supply of encapsulated therapeutic compound (s) at the disease site, e.g., solid tumors.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.particle-works.com/applications/targeted-drug-delivery/
Benefits of using Particle Works nanoparticles for targeted drug delivery. Typically, nanoparticle suppliers provide non-uniform or polydisperse (CV values >20%) material with various particle sizes, shapes and architectures. The targeting efficacy of such materials is substantially diminished. Particle Works offers a range of highly monodisperse...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619175/
Aug 16, 2016 · Targeted nanoparticles are those that contain ligands on their surface and are capable of specifically recognizing cells. In applications against cancer, the promise of targeted nanoparticles is based on the fact that tumors express and/or overexpress some biomarkers, which can be used as targets for drug delivery.Author: Bruno A Cisterna, Nazila Kamaly, Nazila Kamaly, Won Il Choi, Ali Tavakkoli, Omid C Farokhzad, Omid C...
https://www.future-science.com/doi/full/10.4155/fdd-2019-0005
Jul 01, 2019 · Perlecan-targeted nanoparticles showed improved cell uptake, retention, cytotoxicity in vitro and enhanced tumor growth inhibition in vivo. Conclusion: The data presented here indicates that perlecan-targeted nanoparticles can improve tumor drug delivery to TNBC.Author: Vidhi Khanna, Stephen Kalscheuer, Ameya Kirtane, Wenqiu Zhang, Jayanth Panyam
http://www.frontiermaterials.net/teaching/pubs/targeted_nanoparticles_bbb.pdf
Targeted nanoparticles for drug delivery through the blood–brain barrier for Alzheimer’s diseaseB Celeste Roney a, Padmakar Kulkarni a, Veera Arora a, Peter Antich a, Frederick Bonte a, Aimei Wu b, N.N. Mallikarjuana b, Sanjeev Manohar b, Hsiang-Fa Liang c, Anandrao R. Kulkarni c, Hsing-Wen Sung c, Malladi Sairam d, Tejraj M. Aminabhavi d,* a Department of Radiology, Division of Advanced ...
https://www.hindawi.com/journals/jnm/2016/1087250/
A typical drug delivery nanoparticle starts with a nanoplatform class, which include liposomes, polymeric micelles, drug conjugated polymers, and dendrimers [4–7]. There are three main methods to transport drug-loaded nanoparticles to diseased sites: passive targeting, active targeting, and physical targeting.Author: Xiaojiao Yu, Ian Trase, Muqing Ren, Kayla Duval, Xing Guo, Zi Chen
https://www.sciencedirect.com/science/article/pii/S0928493115305981
Targeted drug delivery system (TDDS) is applied to precisely target and treat the tumors. Polymeric nanoparticles (PNPs) are used as carrier of anticancer agents in TDDS. The current progress in uses of PNPs in TDDS is addressed in this review.Author: Farha Masood
https://www.sciencedirect.com/science/article/pii/S0165247817301761
Targeted drug delivery by nanomaterials is an effective anti-cancer therapeutic approach. Abstract Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-tumor therapeutic approaches.Author: Behdokht Bahrami, Behdokht Bahrami, Mohammad Hojjat-Farsangi, Mohammad Hojjat-Farsangi, Hamed Mohamm...
https://www.magneticmicrosphere.com/ckfinder/userfiles/files/345_Zhang.pdf
Targeted drug delivery ABSTRACT Targeted drug delivery using magnetic nanoparticles is an efficient technique as molecules can be directed toward specific tissues inside a human body. For the first time, we implemented a real-time imaging-based guidance system of nanoparticles using untethered electro-magnetic devices for simultaneous guiding and
https://www.sciencedirect.com/science/article/pii/S1773224719319112
Apr 11, 2020 · Targeted delivery of antiobesity drugs to adipocytes presents a novel strategy for obesity treatment. The 11 beta-hydroxysteroid dehydrogenase type 1 …
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