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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077137/
Oct 18, 2016 · This review summarizes articles that have been reported in literature on liposome-based strategies for effective drug delivery across the blood–brain barrier. Due to their unique physicochemical characteristics, liposomes have been widely investigated ...Author: Débora B Vieira, Lionel F Gamarra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539328/
Summary: Antibody-conjugated liposomes or immunoliposomes are particulate drug carriers that can be used to direct encapsulated drug molecules to diseased tissues or organs. The present review discusses examples of successful applications of this technology to …Author: Anita Schnyder, Jörg Huwyler
https://www.sciencedirect.com/science/article/pii/S0169409X11002900
5.2. Transport system-mediated drug delivery across the blood–brain barrier. The combination of endogenous transport systems present in the BBB and macromolecular conjugates or surface enhanced nano-particulate delivery systems such as liposomes, nanoparticles and supermolecular complexes has been utilised to access the brain.Author: Yan Chen, Lihong Liu
https://www.researchgate.net/profile/Sandra_Rocha/publication/236456810_Targeted_Drug_Delivery_Across_the_Blood_Brain_Barrier_in_Alzheimer%27s_Disease/links/5469f44c0cf2f5eb18071df5/Targeted-Drug-Delivery-Across-the-Blood-Brain-Barrier-in-Alzheimers-Disease.pdf
Targeted drug delivery across the blood brain barrier in Alzheimer’s disease Sandra Rocha Department of Chemical and Biological Engineering, Chalmers University of Technology, 41296 Gothenburg ...
https://link.springer.com/article/10.1007%2Fs40263-016-0405-9
Jan 18, 2017 · CNS disorders are on the rise despite advancements in our understanding of their pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the blood–brain barrier (BBB), which serves as an arduous janitor to protect the brain. Many drugs are being discovered for CNS disorders, which, however fail to enter the market because of their inability to cross the BBB. …Author: Mayur M. Patel, Bhoomika M. Patel
https://www.researchgate.net/publication/236456810_Targeted_Drug_Delivery_Across_the_Blood_Brain_Barrier_in_Alzheimer's_Disease
Targeted drug delivery across the blood brain barrier in Alzheimer’s disease Sandra Rocha Department of Che mical and Biolog ical Engineering , Chalmers Univer sity of Technol ogy, 41296 Gothe ...
https://phys.org/news/2018-05-nanoparticles-drugs-blood-brain-barrier-glioblastoma.html
May 24, 2018 · "What is unique here is we are not only able to use this mechanism to get across the blood-brain barrier and target tumors very effectively, we are …
https://www.sciencedirect.com/science/article/pii/S0028390816303616
Efficient transcytosis across the blood-brain-barrier (BBB) is an important strategy for accessing drug targets within the central nervous system (CNS). Despite extensive research the number of studies reporting successful delivery of macromolecules or macromolecular complexes to …Author: Imre Mäger, Imre Mäger, Axel H. Meyer, Jinghuan Li, Martin Lenter, Tobias Hildebrandt, German Leparc...
https://link.springer.com/article/10.1007/s13346-019-00679-2
Nov 14, 2019 · The malignant brain cancer, glioblastoma multiforme (GBM), is heterogeneous, infiltrative, and associated with chemo- and radioresistance. Despite pharmacological advances, prognosis is poor. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site.Author: Lynn Jena, Emma McErlean, Helen McCarthy
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