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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533644/
Aug 10, 2015 · The idea behind targeted liposome-based drug delivery to treat breast cancer is generally to first identify an overexpressed cell surface receptor to be targeted. Once identified, a known targeting ligand specific for that cell surface receptor can then be incorporated within either the bilayer of the liposome or at the distal end of the PEG ( Figs. 1 1 – 3 ).Author: David R. Khan, Maggie N. Webb, Thomas H. Cadotte, Madison N. Gavette
https://www.ingentaconnect.com/content/ben/cpd/2004/00000010/00000024/art00007
Delivery of agents to the reticuloendothelial system (RES) is easily achieved, since most conventional liposomes are trapped by the RES. For the purpose of delivery of agents to target organs other than RES, long-circulating liposomes have been developed by modifying the liposomal surface.
https://www.researchgate.net/publication/8334612_Targeted_Liposomal_Drug_Delivery_in_Cancer
Targeted Liposomal Drug Delivery in Cancer Current Pharmaceutical Design, 2004, Vol. 10, No. 24 2985 biopanning was carried out also in a human patient with a goal to identify clinically useful ...
https://www.sciencedirect.com/science/article/pii/S1773224719313097
Biological agents like antigen and drugs can also be encapsulated into liposomes to kill the tumor cells.The present invention revealed the method of liposomal targeted delivery of antigen for modulating immune cells or drugs to target cells . PEGylated liposomes were comprised of an immunostimulatory agent, a diagnostic marker and a maleimide.Author: Shivani Saraf, Ankit Jain, Ankita Tiwari, Amit Verma, Pritish Kumar Panda, Sanjay K. Jain
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1381-6128&volume=10&issue=24&spage=2981
Title: Targeted Liposomal Drug Delivery in Cancer. VOLUME: 10 ISSUE: 24. ... and are utilized as drug carriers in drug delivery systems. In addition, liposomes can be used to carry radioactive compounds as radiotracers can be linked to multiple locations in liposomes. One option is the hydrated compartment inside the liposome, another the lipid ...
https://www.future-science.com/doi/abs/10.4155/fmc-2016-0135
Oct 24, 2016 · Ligand-conjugated liposomes are designed to target receptors which are overexpressed on tumor cells to decrease drugs side effects by enhancing their selective delivery to tumor site. Despite the extensive research in this area, no small molecule ligand-conjugated liposome has been approved up to date for cancer therapy.Author: Shaghayegh Fathi, Adegboyega K Oyelere
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