Targeted Drug Delivery For Cancer

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Targeted drug delivery for cancer therapy: the other side ...

    https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-5-70
    Nov 09, 2012 · In parallel to naked TMAs, antibody-drug conjugates (ADCs) have been developed for targeted delivery of potent anti-cancer drugs with the aim of bypassing the morbidity common to conventional chemotherapy.Author: Michael A Firer, Gary Gellerman

Targeted drug delivery to tumors: Myths, reality and ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272876/
    Aug 10, 2011 · For cancer therapies, the ideal targeted drug delivery system is the one that delivers the drug only to the target tumor. The reality, however, is far away from that ideal scenario. The amount of drug delivered to tumor targets is much less than 5% at most.Author: You Han Bae, Kinam Park

Novel Oncology Therapeutics: Targeted Drug Delivery for Cancer

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819756/
    Oct 22, 2013 · It contains 12 papers embracing most aspects of cancer related to the exploration of active targeted nanoparticles for cancer treatment and diagnosis, including the exploitation of novel cancer drug targets, vaccine design against cancer, innovative methods for drug delivery-based on focused ultrasound or convection enhanced delivery, and mathematical modeling as an …Author: Andreas G. Tzakos, Evangelos Briasoulis, Theresia Thalhammer, Walter Jäger, Vasso Apostolopoulos

Targeted Drug Delivery in Cancer Therapy

    https://journals.sagepub.com/doi/pdf/10.1177/153303460500400405
    specifically targeted drug delivery systems arises from not only the clinical perspective but can also help in eradicating cancer from the patient before it kills the patient.

Nanoparticles and targeted drug delivery in cancer therapy.

    https://www.ncbi.nlm.nih.gov/pubmed/28760499
    It has been shown that conjugation of nanocarriers with molecules such as antibodies and their variable fragments, peptides, nucleic aptamers, vitamins, and carbohydrates can lead to effective targeted drug delivery to cancer cells and thereby cancer attenuation.Author: Behdokht Bahrami, Behdokht Bahrami, Mohammad Hojjat-Farsangi, Mohammad Hojjat-Farsangi, Hamed Mohamm...

Antibody–drug conjugates: targeted drug delivery for cancer

    https://www.sciencedirect.com/science/article/pii/S136759311000075X
    The underlying reason for this has been obtained in pre-clinical biodistribution and pharmacokinetics studies showing that targeted delivery leads to high intratumoral free drug concentrations, while non-target tissues are largely spared from chemotherapeutic exposure.Author: Stephen C Alley, Nicole M Okeley, Peter D Senter

Nanocarriers for cancer-targeted drug delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/26061298
    Nanoparticles as drug delivery system have received much attention in recent years, especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded poorly soluble hydrophobic drugs by solubilizing them in the hydrophobic compartments, nanoparticles allowed cancer specific drug delivery by inherent passive targeting phenomena and adopted active targeting …Author: Preeti Kumari, Balaram Ghosh, Swati Biswas

Controlled drug delivery vehicles for cancer treatment and ...

    https://www.nature.com/articles/s41392-017-0004-3
    Mar 16, 2018 · Recently, multifunctional QDs have been synthesized, making them a promising targeted drug delivery vehicle for the diagnosis and image-guided chemotherapy of various cancers 25,26.Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti

Targeted Cancer Therapies Fact Sheet - National Cancer ...

    https://www.cancer.gov/about-cancer/treatment/types/targeted-therapies/targeted-therapies-fact-sheet
    Targeted cancer therapies are drugs or other substances that block the growth and spread of cancer by interfering with specific molecules ("molecular targets") that are involved in the growth, progression, and spread of cancer. Targeted cancer therapies are sometimes called "molecularly targeted drugs…

How Targeted Therapies Are Used to Treat Cancer

    https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/targeted-therapy/what-is.html
    Targeted therapy drugs, like other drugs used to treat cancer, are technically considered chemotherapy. But targeted therapy drugs don’t work the same way as traditional or standard chemotherapy (chemo) drugs. Targeted drugs zero in on some of the changes that make cancer cells different from normal cells.

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