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https://www.sciencedirect.com/science/article/pii/S1740674911000308
Enhanced permeability and retention (EPR) effect is a popular strategy for targeting nanosize anticancer drugs to tumor tissues. In this review we discuss how EPR effect outcome can be influenced by variables such as tumor diversity, animal models, biodistribution, intracellular interaction, and release rate of active cytotoxic cargo from its nanosize carrier.Author: Khaled Greish, Khaled Greish
https://www.nature.com/articles/s41467-018-03705-y
Apr 12, 2018 · Targeted delivery approaches for cancer therapeutics have shown a steep rise over the past few decades. However, compared to the plethora of …Author: Daniel Rosenblum, Nitin Joshi, Nitin Joshi, Wei Tao, Jeffrey M. Karp, Jeffrey M. Karp, Dan Peer
https://www.azonano.com/article.aspx?ArticleID=4668
Nov 01, 2017 · As fast growing tumors also lack functioning lymphatic systems, the enhanced permeability and retention effect should allow for targeted delivery of chemotherapeutic drugs. Studies have analyzed which types of tumors have responded best to selective drug release via the enhanced permeability and retention effect.Author: Azonano
https://www.sciencedirect.com/topics/medicine-and-dentistry/enhanced-permeability-and-retention-effect
For example, the central regions of metastatic tumors do not have the enhanced permeability and retention effect owing to poor vasculature, which leads to a low accumulation of colloidal AuNSs. Hence, AuNSs alone have insufficient therapeutic efficacy. However, AuNSs’ anticancer efficacy can be improved using a targeted delivery strategy.
https://www.slideshare.net/massimomasserini3/cancer-28652032
Nov 26, 2013 · • In tumors the uptake of NP depends on the so-called enhanced permeability and retention effect (EPR). ... Targeted drug delivery to tumor Tasnim Fariha Noshin. Cancer Chemoprevention and Molecular Targeting Drug Delivery for Cancer Sukriti Singh. Nanoparticle drug-delivery-systems-for-cancer-treatment Aranca. ...
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