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https://pubs.acs.org/doi/10.1021/mp060039w
Jul 12, 2006 · Our results suggest that the ligand targeted and sterically stabilized nanoparticles can provide a selective delivery of AS-ODN and siRNA into lung cancer cells for therapy. Keywords: Targeted delivery; antisense oligodeoxynucleotide; siRNA; survivin; lung cancerAuthor: Shyh Dar Li, Leaf Huang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342499/
Feb 01, 2010 · Targeted Delivery of Antisense Oligodeoxynucleotide by Transferrin Conjugated pH-Sensitive Lipopolyplex Nanoparticles: A Novel Oligonucleotide –Based Therapeutic Strategy in Acute Myeloid LeukemiaAuthor: Yan Jin, Shujun Liu, Bo Yu, Sharon Golan, Chee Guan Koh, Jintao Yang, Lenguyen Huynh, Xiaojuan Yang,...
https://www.ncbi.nlm.nih.gov/pubmed/19852511
Feb 01, 2010 · Targeted delivery of antisense oligodeoxynucleotide by transferrin conjugated pH-sensitive lipopolyplex nanoparticles: a novel oligonucleotide-based therapeutic strategy in acute myeloid leukemia. Jin Y(1), Liu S, Yu B, Golan S, Koh CG, Yang J, Huynh L, Yang X, Pang J, Muthusamy N, Chan KK, Byrd JC, Talmon Y, Lee LJ, Lee RJ, Marcucci G.Author: Yan Jin, Shujun Liu, Bo Yu, Sharon Golan, Chee Guan Koh, Jintao Yang, Lenguyen Huynh, Xiaojuan Yang,...
https://pubs.acs.org/doi/pdf/10.1021/mp900205r
Targeted Delivery of Antisense Oligodeoxynucleotide by Transferrin Conjugated pH-Sensitive Lipopolyplex Nanoparticles: A Novel Oligonucleotide-Based Therapeutic Strategy in …
https://www.researchgate.net/publication/6784699_Targeted_Delivery_of_Antisense_Oligodeoxynucleotide_and_Small_Interference_RNA_into_Lung_Cancer_Cells
Targeted Delivery of Antisense Oligodeoxynucleotide and Small Interference RNA into Lung Cancer Cells. Selective gene inhibition by antisense oligodeoxynucleotide (AS-ODN) or by small interference RNA (siRNA) therapeutics promises the treatment of diseases that …
https://advances.sciencemag.org/content/4/10/eaat3386.full
Oct 01, 2018 · A major advantage of using antisense oligonucleotides (ASOs) for therapeutic interventions is the ability to target genes coding for proteins linked to human diseases that are considered undruggable by classical small-molecule approaches or other traditional modalities (1–3).Author: C. Ämmälä, W. J. Drury, L. Knerr, I. Ahlstedt, P. Stillemark-Billton, C. Wennberg-Huldt, E.-M. Ander...
https://academic.oup.com/nar/article/42/13/8796/1283685
Jul 03, 2014 · The ASGPR has been utilized for the targeted delivery of modified lipoprotein particles , genes , chemically modified oligonucleotides (22,23), siRNA and microRNA antagonists to hepatocytes in rodents.Author: Thazha P. Prakash, Mark J. Graham, Jinghua Yu, Rick Carty, Audrey Low, Alfred Chappell, Karsten Schm...
https://link.springer.com/article/10.1007/s40820-020-0409-3
Mar 17, 2020 · A framework nucleic acid delivery system was developed through self-assembly, which can deliver antisense oligonucleotides against multiple targets in bacterial cells. The ASOs-tFNAs (750 nM) was found to simultaneously inhibit the expression of gtfBCD , gbpB , and ftf , and significantly reduce the extracellular polysaccharide synthesis and biofilm thickness.Author: Yuxin Zhang, Xueping Xie, Wenjuan Ma, Yuxi Zhan, Chenchen Mao, Xiaoru Shao, Yunfeng Lin
https://www.researchgate.net/publication/11852803_Targeted_delivery_of_antisense_oligonucleotides_in_cancer
Here, we tested the in vitro and in vivo antitumor effects of a novel antisense oligodeoxynucleotide (asODN) liposomal formulation, the coated cationic liposomes (CCL), by targeting the c-myc and ...
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