We have collected information about Targeted Delivery Across The Bloodrain Barrier for you. Follow the links to find out details on Targeted Delivery Across The Bloodrain Barrier.
https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/1743-8977-7-3
Mar 03, 2010 · Nanotechnology has brought a variety of new possibilities into biological discovery and clinical practice. In particular, nano-scaled carriers have revolutionalized drug delivery, allowing for therapeutic agents to be selectively targeted on an organ, tissue and cell specific level, also minimizing exposure of healthy tissue to drugs. In this review we discuss and analyze three issues, which ...Author: Sonu Bhaskar, Furong Tian, Tobias Stoeger, Wolfgang G Kreyling, Jesús M. de la Fuente, Valeria Grazú...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140134/
Dec 01, 2010 · Effective delivery of therapeutic agents into the brain can greatly improve the treatments of neurological and neurodegenerative diseases. Application of focused ultrasound facilitated by microbubbles has shown the potential to deliver drugs across the blood–brain barrier into targeted sites within the brain noninvasively.Author: Cheri X Deng
https://www.researchgate.net/publication/7471379_Targeted_delivery_across_the_blood-brain_barrier_Expert_Opin_Drug_Deliv_2299-309
Targeted delivery across the blood-brain barrier. Expert Opin Drug Deliv 2:299-309 ... T argeted delivery across the blood–brain barrier. ... cept of targeted drug delivery to the brain, but not ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493051/
Thus, improving access to the tumor, while leaving normal brain tissue unscathed, is a critical pursuit. A central challenge in this endeavor lies in the limited delivery of therapeutics to the tumor itself. The blood-brain barrier (BBB) is responsible for much of this difficulty but also provides an essential separation from systemic circulation.Author: Tej D. Azad, James Pan, Ian D. Connolly, Austin Remington, Christy M. Wilson, Gerald A. Grant
https://www.sciencedirect.com/science/article/pii/S0028390816303616
Efficient transcytosis across the blood-brain-barrier (BBB) is an important strategy for accessing drug targets within the central nervous system (CNS). Despite extensive research the number of studies reporting successful delivery of macromolecules or macromolecular complexes to …Author: Imre Mäger, Imre Mäger, Axel H. Meyer, Jinghuan Li, Martin Lenter, Tobias Hildebrandt, German Leparc...
https://www.researchgate.net/publication/278674493_Targeted_Drug_Delivery_Overcoming_Barriers_through_the_Design_of_Novel_Delivery_Vehicles
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https://www.future-science.com/doi/10.4155/tde.10.66
Dec 03, 2010 · Effective delivery of therapeutic agents into the brain can greatly improve the treatments of neurological and neurodegenerative diseases. Application of focused ultrasound facilitated by microbubbles has shown the potential to deliver drugs across the blood–brain barrier into targeted sites within the brain noninvasively.Author: Cheri X Deng
https://link.springer.com/article/10.1007%2Fs40263-016-0405-9
Jan 18, 2017 · CNS disorders are on the rise despite advancements in our understanding of their pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the blood–brain barrier (BBB), which serves as an arduous janitor to protect the brain. Many drugs are being discovered for CNS disorders, which, however fail to enter the market because of their inability to cross the BBB. …Author: Mayur M. Patel, Bhoomika M. Patel
https://www.hindawi.com/journals/bmri/2014/869269/
However, tumor necrosis factor receptor-IgG fusion protein is prepared for targeted drug delivery across the human blood brain barrier. The tumor necrosis factor-alpha receptor (TNFR) contains an extracellular domain (ECD) that can be used in neurotherapeutics of stroke, brain injury, or chronic neurodegeneration [101, 110]. As nascent TNFR ECD ...Author: Ravi Kant Upadhyay
https://www.medscape.com/viewarticle/770396_2
Oct 27, 2019 · Nanotechnology may be the key to opening the gate of the blood brain-barrier, providing a significant advantage over currently used drug delivery strategies for …
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