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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149982/
Aug 16, 2010 · Between the two major classifications of administration, local vs. systemic, systemic delivery approaches are often preferred due to ease of administration. However, systemic delivery may result in suboptimal drug concentration being achieved in the CNS, and lead to erroneous conclusions regarding agent efficacy.Author: Laura Serwer, Rintaro Hashizume, Tomoko Ozawa, C. David James
https://www.collinsdictionary.com/dictionary/english/drug-delivery-system
Drug delivery system definition: A drug delivery system is a system that is used as a medium or carrier for administering... Meaning, pronunciation, translations and examples. ... The right drug delivery system will deliver a drug to the right part of the body at the right time.
https://medical-dictionary.thefreedictionary.com/systemic
systemic: [ sis-tem´ik ] pertaining to or affecting the body as a whole. systemic disease one affecting a number of tissues that perform a common function.
https://en.wikipedia.org/wiki/Systemic_administration
Systemic administration is a route of administration of medication, nutrition or other substance into the circulatory system so that the entire body is affected. Administration can take place via enteral administration (absorption of the drug through the gastrointestinal tract) or parenteral administration (generally injection, infusion, or implantation).
https://www.medicinenet.com/script/main/art.asp?articlekey=25440
Dec 21, 2018 · Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body.
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