We have collected information about Systemic Delivery Of Synthetic Sirnas for you. Follow the links to find out details on Systemic Delivery Of Synthetic Sirnas.
https://www.researchgate.net/publication/5367981_Systemic_Delivery_of_Synthetic_siRNAs
Systemic Delivery of Synthetic siRNAs. ... Here, we show that the systemic delivery of plasmid-based ribozymes targeting NF-kappaB in adult, tumor-bearing mice suppressed NF-kappaB expression in ...
https://www.ncbi.nlm.nih.gov/pubmed/20387144
Systemic delivery of synthetic siRNAs. Sørensen DR(1), Sioud M. Author information: (1)Department of Comparative Medicine, Rikshospitalet-Radiumhospitalet, University Hospital, Oslo, Norway. RNA interference is a biological process for gene silencing that can …Author: Dag R. Sørensen, Mouldy Sioud
https://www.sciencedirect.com/science/article/pii/S0022283603001815
In mammalian cells, RNA duplexes of 21–23 nucleotides, known as small interfering RNAs (siRNAs) specifically inhibit gene expression in vitro.Here, we show that systemic delivery of siRNAs can inhibited exogenous and endogenous gene expression in adult mice.Author: Dag R. Sørensen, Marianne Leirdal, Mouldy Sioud
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096447/
Dec 03, 2007 · A number of important lessons can be learned from the seemingly disparate in vivo studies with siRNA. Delivery systems designed to favorably alter the pharmacokinetics and biodistribution of siRNAs are essential for systemic use, as they prolong siRNA half-lives in serum and blood and reduce the effective dose of naked siRNA.Author: Saghir Akhtar, Ibrahim F. Benter
https://link.springer.com/protocol/10.1385/1-59259-746-7:515
This is now driven predominantly by small interfering RNAs (siRNAs) as they induce sequence-specific gene silencing. However, the major obstacle to the use of siRNAs as therapeutics is the difficulty involved in effective in vivo delivery. This chapter describes the liposomal delivery of siRNAs into adult mice.Author: Dag R. Sørensen, Mouldy Sioud
https://www.researchgate.net/publication/10841229_Gene_Silencing_by_Systemic_Delivery_of_Synthetic_siRNAs_in_Adult_Mice
Gene Silencing by Systemic Delivery of Synthetic siRNAs in Adult Mice Article in Journal of Molecular Biology 327(4):761-6 · May 2003 with 34 Reads How we measure 'reads'
https://link.springer.com/protocol/10.1007/978-1-60761-657-3_6
Feb 08, 2010 · Abstract. RNA interference is a biological process for gene silencing that can be harnessed for the development of new drugs. However, a major obstacle to the use of small interfering RNAs (siRNAs) as therapeutics is their delivery across the plasma membrane of cells in vivo.Author: Dag R. Sørensen, Mouldy Sioud
https://www.jci.org/articles/view/33494
Toxicogenomics and genocompatibility of in vivo delivery systems. Optimal systemic delivery should be achieved without compromising siRNA gene-silencing activity and specificity. It has traditionally been thought that drug delivery systems used in siRNA experiments …
https://www.deepdyve.com/lp/elsevier/gene-silencing-by-systemic-delivery-of-synthetic-sirnas-in-adult-mice-SZpG8Mxpnz
Apr 04, 2003 · Read "Gene Silencing by Systemic Delivery of Synthetic siRNAs in Adult Mice, Journal of Molecular Biology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.sciencedirect.com/science/article/pii/S0969996119300609
The ApoB 11 peptide could be used to deliver any form or design of nucleotides including, but not limited to: cDNA, mRNA, siRNA, shRNA, miRNA, gRNA or synthetic nucleotide sequences. Systemic delivery of oligonucleotides to the CNS could be beneficial for neurodegenerative diseases, neuro-modulatory treatments, cancers of the CNS, gene targeted ...Author: Brian Spencer, Ivy Trinh, Edward Rockenstein, Michael Mante, Jazmin Florio, Anthony Adame, Omar M.A....
Searching for Systemic Delivery Of Synthetic Sirnas?
You can just click the links above. The data is collected for you.
