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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341725/
Mucosal routes have thus been proposed to replace parenteral routes, as mucosal administration might be envisaged to provide a non-invasive systemic pathway. Oral, buccal, nasal, pulmonary, transdermal, and vaginal routes are all accepted for systemic biopharmaceutical delivery.
https://www.researchgate.net/publication/224899144_Systemic_delivery_of_biopharmaceuticals_Parenteral_forever
In this chapter we revised the main characteristics that make inhalation a promise route for delivery of biopharmaceuticals, and also the advances seen in the field of pulmonary delivery of this ...Author: Ana Grenha
http://europepmc.org/articles/PMC3341725
Systemic delivery of biopharmaceuticals: Parenteral forever? Ana Grenha Assistant Professor in Pharmaceutics, IBB-Institute for Biotechnology and Bioengineering, Centre for Molecular and Structural Biomedicine, Faculty of Sciences and Technology - University of Algarve, Campus Gambelas, Building 8, Room 2.4, Lab 2.22, 8005-139 Faro, Portugal.
https://core.ac.uk/download/pdf/61504861.pdf
Title: Systemic delivery of biopharmaceuticals: parenteral forever? Article type: Editorial The subject of systemic delivery of biopharmaceuticals has been discussed in some occasions in Journal of Pharmacy and Bioallied Sciences, which is now in its 11th issue. The last decades
https://core.ac.uk/display/61504861
Systemic delivery of biopharmaceuticals: parenteral forever? By Ana Grenha. Abstract. The subject of systemic delivery of biopharmaceuticals has been discussed in some occasions in Journal of Pharmacy and Bioallied Sciences, which is now in its 11th issue. The last decades have witnessed a strong biotechnological progress, making available many ...Author: Ana Grenha
https://www.researchgate.net/publication/260311190_Pulmonary_Delivery_of_Biopharmaceuticals
Pulmonary Delivery of Biopharmaceuticals. ... induces both mucosal and systemic immunity, and the delivery of antigens in a dry powder state can overcome some challenges such as cold-chain and ...
https://link.springer.com/chapter/10.1007%2F978-1-4614-9524-6_7
Feb 04, 2014 · Both local and systemic delivery at therapeutic concentrations could be achieved by inhalation for many macromolecules. In this chapter we revised the main characteristics that make inhalation a promise route for delivery of biopharmaceuticals, and also the advances seen in the field of pulmonary delivery of this type of drugs.Author: Fernanda Andrade, Catarina Moura, Bruno Sarmento
https://www.sciencedirect.com/science/article/pii/S0167779909001437
Therapeutic application of peptides and proteins: parenteral forever? ... The most frequently marketed biopharmaceuticals include monoclonal-antibody-based products for the treatment of different types of ... Peptide and protein drugs have several properties that make their systemic delivery difficult. The generally low bioavailability of ...Author: Zuzana Antosova, Martina Mackova, Vladimir Kral, Tomas Macek
https://www.heighpubs.org/hjb/abb-aid1004.php
May 27, 2017 · Despite the wide range of research regarding the different technologies for the systemic delivery of the biopharmaceuticals, the local delivery of some drugs such as the growth factors is the most suitable way for guaranteed targeting of specific tissues with optimum efficiency.Author: Amir Mohammed Alsharabasy
http://www.biopharminternational.com/drug-delivery-systems-biopharmaceuticals
Aug 01, 2015 · Drug Delivery Systems for Biopharmaceuticals. ... Most biologic products for parenteral administration are freeze-dried in vials to help maintain drug stability and increase shelf life. But interest is growing in the development of liquid formulations in prefilled syringes and autoinjectors, which offer convenience and ease of administration in ...
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