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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202607/
May 01, 2010 · RNA interference (RNAi) is a powerful approach for silencing genes associated with a variety of pathologic conditions; however, in vivo RNAi delivery has remained a major challenge due to lack of safe, efficient, and sustained systemic delivery. Here, we report on a novel approach to overcome these limitations using a multistage vector composed of mesoporous silicon particles (stage 1 ...Author: Takemi Tanaka, Takemi Tanaka, Lingegowda S. Mangala, Pablo E. Vivas-Mejia, René Nieves-Alicea, Aman ...
https://www.ncbi.nlm.nih.gov/pubmed/20430760
May 01, 2010 · Sustained small interfering RNA delivery by mesoporous silicon particles. ... in vivo RNAi delivery has remained a major challenge due to lack of safe, efficient, and sustained systemic delivery. Here, we report on a novel approach to overcome these limitations using a multistage vector composed of mesoporous silicon particles (stage 1 ...Author: Takemi Tanaka, Takemi Tanaka, Lingegowda S. Mangala, Pablo E. Vivas-Mejia, René Nieves-Alicea, Aman ...
https://www.researchgate.net/publication/43354714_Sustained_Small_Interfering_RNA_Delivery_by_Mesoporous_Silicon_Particles
Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles. ... and sustained systemic delivery. Here, we report on a novel approach to overcome these limitations using a multistage ...
https://cancerres.aacrjournals.org/content/canres/70/9/3687.full-text.pdf
sustained systemic delivery. Here, we report on a novel approach to overcome these limitations using a multi-stage vector composed of mesoporous silicon particles (stage 1 microparticles, S1MP) loaded with neutral nanoliposomes (dioleoyl phosphatidylcholine, DOPC) containing small interfering RNA …
https://www.researchgate.net/publication/255178238_Mesoporous_Silicon_Particles_for_Sustained_Gene_Silencing
Here, we describe a novel approach to overcome these limitations using mesoporous silicon particles loaded with nanoparticles (i.e., liposomes) containing small interfering RNA (siRNA) targeted ...
https://www.academia.edu/9535205/Sustained_Small_Interfering_RNA_Delivery_by_Mesoporous_Silicon_Particles
Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles
https://scholars.houstonmethodist.org/en/publications/sustained-small-interfering-rna-delivery-by-mesoporous-silicon-particles(a2cd7cf8-b0c7-4871-a11b-1a27f5255a2b).html
Takemi Tanaka, Lingegowda S. Mangala, Pablo E. Vivas-Mejia, René Nieves-Alicea, Aman P. Mann, Edna Mora, Hee Dong Han, Mian M.K. Shahzad, Xuewu Liu, Rohan Bhavane ...Author: Takemi Tanaka, Takemi Tanaka, Lingegowda S. Mangala, Pablo E. Vivas-Mejia, René Nieves-Alicea, Aman ...
https://link.springer.com/protocol/10.1007/978-1-62703-547-7_36
Jun 24, 2013 · RNA interference Small interfering RNA Nanoparticle Liposome Multistage delivery Ovarian cancer Sustained gene silencing Mesoporous silicon particle This is a preview of subscription content, log in to check access.Author: Nafis Hasan, Aman Mann, Mauro Ferrari, Takemi Tanaka
https://www.sciencedirect.com/science/article/pii/S1742706118303337
A low toxicity and efficient delivery system is needed to deliver small interfering RNAs (siRNA) in vitro and in vivo.The use of mesoporous silica nanoparticles (MSN) is becoming increasingly common due to its biocompatibility, tunable pore size and customizable properties.Author: Coline Pinese, Coline Pinese, Junquan Lin, Ulla Milbreta, Mingqiang Li, Yucai Wang, Kam W. Leong, Si...
https://www.sciencedaily.com/releases/2010/05/100505143130.htm
May 07, 2010 · The study, which is titled "Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles," received support from the Department of Defense, the State of Texas Emerging Technology Fund ...
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