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https://science.sciencemag.org/content/281/5380/1161.full
Aug 21, 1998 · A variety of approaches for improved delivery of therapeutic proteins are being explored in academia, government labs, and industry. One interesting approach is an injectable, biodegradable system that provides a sustained release of the agent over time.Author: Raymond T. Bartus, Mark A. Tracy, Dwaine F. Emerich, Stephen E. Zale
https://www.researchgate.net/publication/13550843_Sustained_delivery_of_proteins_for_novel_therapeutic_agents
Sustained delivery of proteins for novel therapeutic agents Article (PDF Available) in Science 281(5380):1161-2 · September 1998 with 33 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857543/
When compared to the small molecule drugs, therapeutic proteins and peptides need special formulation strategies to become viable therapeutic protein products. As discussed above, various forms of micro/nanoparticulate drug delivery systems have been explored for …Author: Dipak S. Pisal, Matthew P. Kosloski, Sathy V. Balu-Iyer
https://www.sciencedirect.com/science/article/pii/S0022354915316981
Protein instability and immunogenicity are two main roadblocks to the clinical success of novel protein drug delivery systems. In this commentary, we discuss the need for more extensive analytical characterization in relation to concerns about protein instability in injectable drug delivery systems for sustained release.Author: Wim Jiskoot, Theodore W. Randolph, David B. Volkin, C. Russell Middaugh, Christian Schöneich, Gerhar...
https://www.researchgate.net/publication/40848801_Delivery_of_Therapeutic_Proteins
Delivery of Therapeutic Proteins. ... a novel therapeutic module has been fabricated by coating a nontoxic, biodegradable chitosan nanoparticle core with engineered macrophage membrane-tethered ...
https://www.sciencedirect.com/science/article/pii/S0022354915326241
When compared to the small molecule drugs, therapeutic proteins and peptides need special formulation strategies to become viable therapeutic protein products. As discussed above, various forms of micro/nanoparticulate drug delivery systems have been explored for …Author: Dipak S. Pisal, Matthew P. Kosloski, Sathy V. Balu-Iyer
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