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https://www.researchgate.net/publication/6524067_Study_on_a_Nanoparticle_System_for_Buccal_Delivery_of_Insulin
In this paper, a nanoparticle system of insulin (NSI) was prepared for buccal transmucosal delivery of insulin. The average size of the suspending particles was 67.5 nm, and a possible ...
https://www.ncbi.nlm.nih.gov/pubmed/17281326
In this paper, a nanoparticle system of insulin (NSI) was prepared for buccal transmucosal delivery of insulin. The average size of the suspending particles was 67.5 nm, and a possible microstructure of the nanoparticles in the system was proposed.Author: Yong Luo, Huibi Xu, Kaixun Huang, Zhonghong Gao, Hong Peng, Xiqun Sheng
https://www.sciencedirect.com/science/article/pii/S0168365917308283
Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment. ... In this study, an insulin-phospholipid complex was prepared by an anhydrous co-solvent lyophilisation procedure. ... A two-stage PLGA/Eudragit® RS nanoparticle delivery system coated with HPMCP-55 further improved the enzymatic protection of insulin ...Author: Chun Y. Wong, Hani Al-Salami, Crispin R. Dass
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/nanoparticle-insulin-drug-delivery-applications-and-new-aspects
Insulin is a key player in lowering blood glucose levels for type 1 diabetes and also required at later stages in type 2 diabetes patients. The widely accepted route for delivery of insulin is by parenteral administration but this delivery of insulin usually requires at least three or four daily insulin injections for good glycemic control.Author: Hatice Kübra Elçioğlu, Ali Demir Sezer
https://www.sciencedirect.com/science/article/pii/S0168365920300146
In a different study, a delivery system was developed to increase the buccal permeability for therapeutic peptides, using insulin as drug model . The buccal permeability for peptides is rather low (0.1–5.0%) mainly due to high molecular weight and stability problems, which justifies the use of nanoparticles to enhance permeability [ 151 , 152 ].Author: Ana S. Macedo, Ana S. Macedo, Pedro M. Castro, Luís Roque, Natália G. Thomé, Catarina P. Reis, Manue...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
Insulin delivery methods: Past, present and future. ... (TS) system suspends the delivery of insulin for up to 2 h if a patient does not take action with a low glucose alarm. This feature is designed to reduce the severity and duration of ... Buccal delivery of insulin has similar benefits as oral insulin with the advantage of bypassing GI ...
http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.ieee-000001615556
In this paper, a nanoparticle system of insulin (NSI) was prepared for buccal transmucosal delivery of insulin. The average size of the suspending particles was 67.5 nm, and a possible microstructure of the nanoparticles in the system was proposed.
https://www.researchgate.net/publication/230078371_Buccal_delivery_of_insulin_The_time_is_now
Buccal delivery of insulin: The time is now ... This has led to a battery of needle-free insulin delivery systems. Buccal delivery stands out as being safe, simple, fast, flexible, and familiar to ...Author: Gerald Bernstein
https://www.hindawi.com/journals/jphar/2014/378048/
Y. Luo, H. Xu, K. Huang, Z. Gao, H. Peng, and X. Sheng, “Study on a nanoparticle system for buccal delivery of insulin,” in Proceedings of the 27th IEEE Annual International Conference of the Engineering in Medicine and Biology Society (IEEE-EMBS '05), pp. …Author: Arun Verma, Nitin Kumar, Rishabha Malviya, Pramod Kumar Sharma
https://link.springer.com/article/10.1007%2Fs11095-014-1485-1
Aug 29, 2014 · Enhancing the Buccal Mucosal Delivery of Peptide and Protein Therapeutics ... Huang K, Gao Z, Peng H, Sheng X. Study on a nanoparticle system for buccal delivery of insulin. Conf Proc IEEE Eng Med Biol Soc. 2005;5:4842–5. ... Caon, T., Jin, L., Simões, C.M.O. et al. Enhancing the Buccal Mucosal Delivery of Peptide and Protein Therapeutics ...Author: Thiago Caon, Thiago Caon, Liang Jin, M O Claudia Simoes, Raymond Stanley Norton, Joseph Nicolazzo
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