Solid Self Microemulsifying Drug Delivery System

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Design and optimization of chlordiazepoxide solid self ...

    https://www.researchgate.net/publication/270281556_Design_and_optimization_of_chlordiazepoxide_solid_self-microemulsifying_drug_delivery_system
    The objective of the present study was to design and optimized chlordiazepoxide solid self microemulsifying drug delivery system prepared via spray drying for oral administration.

Solid self-microemulsifying drug delivery system of ...

    https://www.sciencedirect.com/science/article/pii/S0928098719302167
    Aug 01, 2019 · The purpose of this study was to develop a drug delivery system in order to improve oral bioavailability of SFG. The optimum formulation of Self-microemulsifying Drug Delivery System with SFG (SFG-SMEDDS) was selected by the solubility test, self-emulsifying grading test and ternary phase diagram test.

Comparison of solid self-microemulsifying drug delivery ...

    https://www.sciencedirect.com/science/article/pii/S0378517311008313
    In order to compare the effects of hydrophilic and hydrophobic solid carrier on the formation of solid self-microemulsifying drug delivery system (SMEDDS), two solid SMEDDS formulations were prepared by spray-drying the solutions containing liquid SMEDDS and solid carriers.

Solid self-microemulsifying drug delivery system of ...

    https://www.tandfonline.com/doi/abs/10.3109/03639045.2013.768632
    The present study is aimed to enhance the dissolution and oral bioavailability of water-insoluble RTV using the Solid Self-Microemulsifying Drug Delivery System (S-SMEDDS). Objective: To enhance the dissolution and oral bioavailability of water-insoluble RTV using the S-SMEDDS.

Solid self-microemulsifying drug delivery system of ...

    https://www.researchgate.net/publication/235879207_Solid_self-microemulsifying_drug_delivery_system_of_ritonavir
    The aim of this work was to establish a method for preparing stable and controllable solid self-microemulsifying drug delivery system (S-SMEDDS) by spherical crystallization technique, which …

Prospectives of Solid Self-microemulsifying Systems in ...

    http://www.eurekaselect.com/145047/article
    Self-microemulsifying drug delivery systems (SMEDDS) have gained much attention. These are isotropic mixtures of different components (oil, surfactant and cosurfactant) that quickly disperse in gastrointestinal fluid yielding micro/nano-emulsions.

FORMULATION AND EVALUATION OF SOLID SELF …

    https://pdfs.semanticscholar.org/a7ad/c20891ad5b7a4dde9b2d1d7ff99444245935.pdf
    FORMULATION AND EVALUATION OF SOLID SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM Ph.D. Synopsis Submitted To Gujarat Technological University For The Degree Of Doctor of Philosophy In Pharmacy/Pharmacuetics By Miss Jill Bhadreshkumar Shukla 119997290015 SUPERVISOR: DR. GIRISH K JANI PRINCIPAL, SSR COLLEGE OF PHARMACY, SILVASSA …

Formulation and development of solid self ... - SpringerLink

    https://link.springer.com/article/10.1007%2Fs40005-016-0243-2
    Mar 30, 2016 · The objective of the present study was to develop a self micro-emulsifying drug delivery system (SMEDDS) of chlorthalidone (CTD) to improve its solubility and dissolution. CTD is a diuretic agent belongs to Biopharmaceutics classification system (BCS)-IV category having poor solubility and permeability. Solubility study of CTD was carried out in various excipients. Based on …

Self Micro Emulsifying Drug Delivery System

    https://www.slideshare.net/sagarsavale1/self-micro-emulsifying-drug-delivery-system
    Sep 06, 2015 · Conclusion Self-microemulsifying drug delivery system is a novel approach for the formulation of drug compounds with poor aqueous solubility. Self micro emulsifying drug delivery systems (SMEDDS) are mixtures of oils, Cosolvents and surfactants, which is isotropic in nature.

Development and Optimization of Piroxicam-loaded Solid ...

    https://www.ijpsonline.com/articles/development-and-optimization-of-piroxicamloaded-solid-selfmicro-emulsifying-drug-delivery-system.pdf
    Pattewar, et al.: Piroxicam-loaded solid self-microemulsifying drug delivery system The aim of present study was to formulate and evaluate self-microemulsifying drug delivery system containing piroxicam and to use the ability of porous magnesium alumina metasilicate as a solid carrier for self-microemulsifying drug delivery system.

Formulation Design of Self-Microemulsifying Drug Delivery ...

    https://www.jstage.jst.go.jp/article/bpb/27/12/27_12_1993/_pdf/-char/en
    formulating the drug in lipid-based systems. Among the lipid-based systems, self-microemulsifying drug delivery system (SMEDDS) is a promising technology to improve the rate and extent of the absorption of poor-ly water-soluble drugs.8—15) The clinical usefulness of the SMEDDS is evident from the commercially available formu-

Self-microemulsifying drug delivery system - Wikipedia

    https://en.wikipedia.org/wiki/Self-microemulsifying_drug_delivery_system
    A self-microemulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a microemulsion achieved by chemical rather than mechanical means. That is, by an intrinsic property of the drug formulation, rather than by special mixing and handling. It employs the familiar ouzo effect displayed by anethole in many anise-flavored liquors.

A SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM …

    https://pdfs.semanticscholar.org/746a/5a974d3cea1c584e8e80b1ef4a51c952e2a2.pdf
    case. The fact that almost 40% of the new drug compounds are hydrophobic in nature implies that studies with SMEDDS will continue, and more drug compounds formulated as SMEDDS will reach the pharmaceutical market in the future. Keywords: Self-microemulsifying drug delivery systems (SMEDDSs), Lipophillic compound, Droplet Size, Oral Bioavailability.

SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW ...

    http://ijpsr.com/bft-article/self-emulsifying-drug-delivery-system-a-review/?view=fulltext
    Kang B K, et al: Development of self‐microemulsifying drug delivery systems for oral bioavailability enhancement of simvastatin in beagle dogs. International Journal of Pharmaceutics 2004; 274: 65–73. Patil PR, et al: Self Emulsifying Drug Delivery System: A Review. Research Journal of Pharmacy and Technology 2008; 1(4): 313-323.

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