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https://www.sciencedirect.com/science/article/pii/B9780128122181000087
Nanoparticles are classified as: solid lipid nanoparticles (SLNs), nanostructure lipid carriers, and lipid drug conjugates. Of these, the SLNs, which consist of spherical solid lipid particles in the nanometer range, are most easily dispersed in water or aqueous surfactant solution and have the potential to carry lipophilic or hydrophilic drug(s) or diagnostics to the brain.Author: Samir G. Patel, Meghal D. Patel, Archita J. Patel, Mahavir B. Chougule, Hira Choudhury
https://www.ncbi.nlm.nih.gov/pubmed/17570559
Jul 10, 2007 · The available literature on solid lipid nanoparticles and related carriers for brain drug targeting is revised as well. The potential advantages of the use of solid lipid nanoparticles over polymeric nanoparticles are accounted on the bases of a lower cytotoxicity, higher drug loading capacity, and best production scalability.Author: Paolo Blasi, Stefano Giovagnoli, Aurelie Marie Madeleine Schoubben, Maurizio Ricci, Carlo Rossi
https://www.sciencedirect.com/science/article/abs/pii/S0169409X07000427
The present review discusses the potential use of solid lipid nanoparticles for brain drug targeting purposes. The state of the art on surfactant-coated poly(alkylcyanoacrylate) nanoparticles specifically designed for brain targeting is given by emphasizing the transfer of this technology to solid lipid matrices.Author: Paolo Blasi, Stefano Giovagnoli, Aurelie Marie Madeleine Schoubben, Maurizio Ricci, Carlo Rossi
https://www.researchgate.net/publication/6265796_Solid_Lipid_Nanoparticles_for_Targeted_Brain_Drug_Delivery
Solid lipid nanoparticles can be applied for targeted drug delivery, controlled drug delivery and also can be surface-functionalized with polymeric coating or ligand grating for targeting drugs ...
https://www.researchgate.net/publication/324939243_Solid_Lipid_Nanoparticles_for_Targeted_Brain_Drug_Delivery
The aim of the work was to assess the long-term stability and the safety of lipid nanoparticles intended for brain drug delivery. Lipid nanoparticles, prepared by high pressure homogenization ...
https://iopscience.iop.org/article/10.1088/0957-4484/26/49/495103/pdf
[7, 8]. Since the 1990s solid lipid nanoparticles (SLNs) have shown to be very promising for drug delivery in the brain. These spherical particles are composed of biodegradable and biocompatible excipients and are produced from solid lipids with melting points higher than body temperature, remaining in a solid state after administration [1, 9].Author: Ana Rute Neves, Joana Fontes Queiroz, Babette Weksler, Ignacio A Romero, Pierre-Olivier Couraud, Sal...
https://www.sciencedirect.com/science/article/pii/B9780128097175000105
Considering this, Solid lipid nanoparticles have attracted huge attention for the successful delivery of drugs and genes and also employed as an effective strategy for targeting therapeutics. The potential advantages of solid lipid nanoparticles over other nanoparticles are because of their high biocompatibility,...Author: Rakesh K. Tekade, Rahul Maheshwari, Muktika Tekade, Mahavir B. Chougule
https://www.ncbi.nlm.nih.gov/pubmed/26574295
Dec 11, 2015 · Solid lipid nanoparticles as a vehicle for brain-targeted drug delivery: two new strategies of functionalization with apolipoprotein E. Neves AR(1), Queiroz JF, Weksler B, Romero IA, Couraud PO, Reis S.Author: Ana Rute Neves, Joana Fontes Queiroz, Babette Weksler, Ignacio A Romero, Pierre-Olivier Couraud, Sal...
http://pharmaquest.weebly.com/uploads/9/9/4/2/9942916/solid_lipid_nanoparticles_for_targeted_brain_drug_delivery.pdf
The present review discusses the potential use of solid lipid nanoparticles for brain drug targeting purposes. The state of the art on surfactant-coated poly(alkylcyanoacrylate) nanoparticles specifically designed for brain targeting is given by emphasizing the transfer of this technology to solid lipid matrices.
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