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https://www.researchgate.net/publication/327107515_Solid_Lipid_Nanoparticles_A_potential_approach_in_drug_delivery_system
To improve the solubility and bioavailability of solid lipid nanoparticles (SLNs) are the new approach in drug delivery system. Since a decade, a lot of research works are performed to utilize ...
https://www.slideshare.net/anay_ict/solid-lipid-nanoparticles
Mar 25, 2012 · REFERENCES• Solid Lipid Nanoparticles: A Modern Formulation Approach in Drug Delivery System S. MUKHERJEE*, S. RAY AND R. S. THAKUR• Solid Lipid Nanoparticles: Technological Developments and in Vivo Techniques to Evaluate Their Interaction with the Skin Mariella Bleve, Franca Pavanetto and Paola Perugini Department of Drug Sciences ...
https://pubs.acs.org/doi/10.1021/mp200109m
Targeted solid lipid nanoparticles with peptide ligand for oral delivery of atorvastatin calcium. RSC Advances 2016, 6 (42) , 35901-35909. DOI: 10.1039/C6RA02371A. Hailong Zhang, Jie Mi, Yayu Huo, Xiaoyan Huang, Jianfeng Xing, Akira Yamamoto, Yang Gao.
https://www.dovepress.com/surface-modified-solid-lipid-nanoparticles-for-oral-delivery-of-doceta-peer-reviewed-fulltext-article-IJN
Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake Hyun-Jong Cho1, Jin Woo Park2, In-Soo Yoon2, Dae-Duk Kim31College of Pharmacy, Kangwon National University, Chuncheon, 2College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Jeonnam, 3College of Pharmacy and …
http://www.icpjonline.com/documents/Vol1Issue11/08.pdf
advantages of nanoparticles as drug delivery systems are that they are biodegradable, non-toxic, and capable of being stored for longer periods as they are more stable (Chowdary et al., 1997). Since a decade, trials are being made to utilize solid lipid nanoparticles (SLN) as alternative drug delivery
https://www.ijpsonline.com/articles/simvastatin-solid-lipid-nanoparticles-for-oral-delivery-formulation-development-and-in-vivo-evaluation.pdf
self‑nanoemulsifying (SNEDDS) drug delivery systems, and solid lipid nanoparticles for improving oral bioavailability of drugs has been substantially successful. The increase in bioavailability is mainly attributed to increased dissolution of drug, increase in residence time, and lymphatic uptake[2]. Solid lipid nanoparticles (SLNs) developed ...
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.6b00691
Oral delivery of anticancer drugs remains challenging despite the most convenient route of drug administration. Hydrophobicity and nonspecific toxicities of anticancer agents are major impediments in the development of oral formulation. In this study, we developed wheat germ agglutinin (WGA)-conjugated, solid lipid nanoparticles to improve the oral delivery of the hydrophobic anticancer drug ...
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2014.914986
hepatic first-pass metabolism and to enhance oral bioavail-ability, lipid–based drug delivery systems like solid lipid nanoparticles can be used. These systems enhance the lymphatic transport of the lipophilic drugs and therefore increase the bioavailability (Uner & Yener, 2007). SLNs were reported as an alternative drug delivery system
https://gavinpublishers.com/articles/short-commentary/Nanomedicine-and-Nanoscience-Research/solid-lipid-nanoparticles-SLN-for-oral-drug-delivery-an-overview
Solid lipid nanoparticles were introduced in early 1990s, as an effort to enhance the bioavailability of poorly water-soluble drugs [2]. Solid lipid nanoparticles combine the advantages of both the drug delivery systems: nanoparticles and lipid emulsion. They are formulated with lipids which are solid at body temperature and at the room ...
https://www.tandfonline.com/doi/abs/10.1517/17425247.2011.604311
Solid lipid nanoparticles (SLNs) have emerged as potential BA enhancer vehicles for various Class II, III and IV drug molecules. Area covered: This review examines the recent advancements in SLN technology, with regards to oral drug delivery. The discussion critically examines the effect of various key constituents on SLN absorption and their ...
http://pubs.sciepub.com/ajps/2/5A/1/index.html
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics. The ability to incorporate drugs into nanoparticles offers a new prototype in drug delivery thus realizing the dual goal of both controlled release and site-specific drug delivery. Drug ...
https://www.pharmaexcipients.com/news/nanostructured-lipid-carriers/
Oral chemotherapy is the most accepted alternative way, but some anticancer drugs have low oral bioavailability. Nowadays, nanoparticles have received much attention, and solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have achieved an important place in oral cancer drug delivery.
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c4ra15802d
Rosmarinic acid is a polyphenol with described bioactivities, such as antioxidant, anti-mutagenic, anti-bacterial and anti-viral capabilities. Thus, the aim of this research work was to produce stable solid lipid nanoparticles (SLN) using carnauba wax as lipidic matrix, for delivery of rosmarinic acid, to be further incorporated into food matrices.
https://pubs.rsc.org/en/content/articlelanding/2016/nr/c5nr07474f#!divAbstract
Whether and to what extent solid lipid nanoparticles (SLNs) can be absorbed integrally via oral delivery should be clarified because it is the basis for elucidation of absorption mechanisms. To address this topic, the in vivo fate of SLNs as well as their interaction with biomembranes is investigated using w
https://www.recentpatentsonnanomedicine.com/articles/179601/solid-lipid-nanoparticles-for-oral-drug-delivery-a-review
Solid Lipid Nanoparticles for Oral Drug Delivery: A Review Author(s): Manish Gautama, Madhu Verma*, Iti Chauhan, Mohd. Yasir, Alok Pratap Singh and Pawan Kumar Saraswat Pages 1 - 17 ( 17 )
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