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http://www.scielo.br/pdf/bjps/v46n1/02.pdf
Mucoadhesive drug delivery systems 3 the contact between the mucoadhesive and the mucous membrane, with spreading and swelling of the formu-lation, initiating its deep contact with the mucus layer (Hägerstrom, 2003). In some cases, such as for ocular or vaginal formulations, the delivery system is mechanically attached over the membrane.
http://www.revistas.usp.br/bjps/article/view/10749
Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to a bioavailability increase and both local and …
http://www.scielo.br/pdf/bjps/v52n4/2175-9790-bjps-52-04-00715.pdf
drug bioavailability (Varatharajan, Thomas, 2009). Mucoadhesive systems exploit the interaction between formulations containing polymers and the mucus layer that covers epithelial surfaces throughout the body. Due to their increased retention time and closer contact with the absorption site, mucoadhesive systems provideAuthor: Liliane Neves Pedreiro, Beatriz Stringhetti Ferreira Cury, Marco Vinícius Chaud, Maria Palmira Daflo...
http://www.revistas.usp.br/bjps/article/view/128425
In vitro drug dissolution, mucoadhesiveness and AZT intestinal permeability were also determined. Thermal behavior and X-ray diffraction patterns demonstrated the amorphous state of AZT in SD systems. The HPMCP polymer restricted the liquid uptake ability in the acid medium; however, this property significantly increased with higher pH values.Author: Liliane Neves Pedreiro, Beatriz Stringhetti Ferreira Cury, Marco Vinícius Chaud, Maria Palmira Daflo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive drug delivery systems prolong the residence time of the dosage form at the site of application or absorption. They facilitate an intimate contact of the dosage form with the underlying absorption surface and thus improve the therapeutic performance of the drug.
https://www.researchgate.net/publication/221750117_Mucoadhesive_drug_delivery_system_An_overview
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Vaginal Mucoadhesive Drug Delivery Systems. The vagina is a fibrovascular tube connecting the uterus to the outer surface of the body. The vaginal epithelium consists of a stratified squamous epithelium and lamina propia. Dosage forms used for vaginal route are solutions, gels, suspensions, suppositories, creams,...
https://www.researchgate.net/publication/319563818_A_SYSTEMATIC_REVIEW_ON_MUCOADHESIVE_DRUG_DELIVERY_SYSTEM
Sep 01, 2017 · disadvantages of mucoadhesive drug delivery systems [3,35-39] • Drugs irritatinge the oral mucosa, having an unpl easant taste, odor or unstable at buccal pH …Author: Hemal Tandel
http://www.authorstream.com/Presentation/rosecrx-1830872-mucoadhesive-drug-delivery-system/
May 27, 2013 · Mucoadhesive drug delivery system (MDDS): MDDS utilizes the property of bioahesion of certain water-soluble polymers which become adhesive on hydration and hence can be used for targeting a drug to a particular region of the …
https://www.slideshare.net/MUHEEM_007/mucoadhesive-drug-delivery-system
Feb 24, 2013 · What is Mucoadhesive drug delivery system? •Mucoadhesive drug delivery system interact with the mucus layer covering the mucosal epithelial surface, & mucin molecules & increase the residence time of the dosage form at the site of the …
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