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https://www.ncbi.nlm.nih.gov/pubmed/10840199
Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. Müller RH(1), Mäder K, Gohla S. Author information: (1)Department of Pharmaceutical Technology, Biopharmaceutics and Biotechnology, Free University of Berlin, D-12169, Berlin, Germany. Solid lipid nanoparticles...Author: Rainer H. Müller, Karsten Mäder, Sven Gohla
https://www.sciencedirect.com/science/article/pii/S0939641100000874
Intelligent SLN means that the SLN releases in a controlled way the incorporated drug/active ingredient after it receives a triggering impulse. Such triggering impulses are the increase in temperature or the loss of water from an SLN dispersion or an SLN-containing cream.Author: Rainer H. Müller, Karsten Mäder, Sven Gohla
https://www.sciencedirect.com/science/article/pii/S0939641197001501
For prednisolone (nominal drug percentage in the dispersion: 1%), 71% of drug was entrapped in case of the cholesterol SLN and 80% in case of Compritol SLN formulations. In case of prednisolone loaded cholesterol and Compritol SLN formulations, which were used in this investigations, the SLN contained therefore 0.71 and 0.85% drug in the matrix, respectively ( Table 1 ).Author: Annette zur Mühlen, Cora Schwarz, Wolfgang Mehnert
https://www.tandfonline.com/doi/abs/10.1080/026520499289185
Sep 29, 2008 · Solid lipid nanoparticles (SLN) are a colloidal carrier system for controlled drug delivery. The lipophilic model drugs tetracaine and etomidate were incorporated to study the maximum drug loading, entrapment efficacy, effect of drug incorporation on SLN size, zeta potential (charge) and long-term physical stability.Author: Schwarz C, Mehnert W
https://www.researchgate.net/publication/12478490_Solid_Lipid_Nanoparticles_SLN_for_controlled_drug_delivery-A_review_of_the_state_of_the_art
SLNs are nanometer sized particulate drug delivery systems, typically ranging in size from 50-100 nm. Such nanoparticle systems are an advancement over conventional drug delivery systems such as...
http://www.icpjonline.com/documents/Vol1Issue11/08.pdf
Solid lipid nanoparticles (SLN) have emerged as a next-generation drug delivery system with potential applications in pharmaceutical field, cosmetics, research, clinical medicine and other allied sciences. Recently, increasing attention has been focused on these SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs.
http://ijpsr.com/bft-article/solid-lipid-nanoparticles-an-advanced-drug-delivery-system/?view=fulltext
Solid lipid nanoparticle (SLN) dispersions have been proposed as a new type of colloidal drug carrier system suitable for intravenous administration. Solid lipid nanoparticles (SLNs) technology represents a promising new approach to lipophilic drug delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865805/
Keywords: Solid lipid nanoparticles (SLN), colloidal drug carriers, homogenization, TEM, PCS, biodistribution, targeting Colloidal particles ranging in size between 10 and 1000 nm are known as …
https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain
Nanoparticles for drug delivery to the brain is a method for transporting drug molecules across the blood–brain barrier (BBB) using nanoparticles.These drugs cross the BBB and deliver pharmaceuticals to the brain for therapeutic treatment of neurological disorders.
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