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https://www.tandfonline.com/doi/full/10.1080/10717540500455975
Jul 09, 2014 · Parameters that affect design of an iontophoretic skin delivery system include electrode type, current intensity, pH of the system, competitive ion effect, and permeant type (Banga, Bose and Ghosh 1999 , , . Iontophoresis and electroporation: comparisons and contrasts.Author: Marc B. Brown, Gary P. Martin, Stuart A. Jones, Franklin K. Akomeah
https://www.sciencedirect.com/science/article/pii/S0169409X18303181
Drug delivery systems across the nano, micro, and macroscales can extend half-life, improve bioavailability, optimize pharmacokinetics, and decrease dosing frequency of drugs and genes. Replacement of the damaged skin tissue with substitutes comprising cell-laden scaffold can also restore the barrier and regulatory functions of skin at the wound site.Author: Hye Sung Kim, Hye Sung Kim, Xiaoyan Sun, Jung-Hwan Lee, Hae-Won Kim, Xiaobing Fu, Kam W. Leong, Kam ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Today, there are 19 transdermal delivery systems for such drugs as estradiol, fentanyl, lidocaine and testosterone; combination patches containing more than one drug for contraception and hormone replacement; and iontophoretic and ultrasonic delivery systems for analgesia (Table 1, Fig. 1). Between 1979 and 2002, a new patch was approved on average every 2.2 years.Author: Mark R Prausnitz, Robert Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588690/
Sep 30, 2015 · Novel topical drug delivery systems, with the use of nanotechnology in dosage form design, have been used to facilitate overcoming the skin barrier. This article will summarize recent findings of lipid-based nano-delivery systems for skin delivery of drugs and bioactives agents.Author: Susan Hua
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-019-0514-y
Jul 10, 2019 · In particular, the nano-drug delivery systems anchor bioactive molecules to applied area, sustain the drug release and explicitly enhance the therapeutic efficacies of drugs, thus making a fine figure in field relevant to skin regeneration.Author: Wei Wang, Kong-jun Lu, Chao-heng Yu, Qiao-ling Huang, Yong-Zhong Du
https://www.researchgate.net/publication/276837593_The_Structure_of_Skin_and_Transdermal_Drug_Delivery_System-A_Review
The major challenge in designing transdermal drug delivery systems is to overcome the natural transport barrier of the skin. One approach is the use of vesicle formulations.
https://www.sciencedirect.com/science/article/pii/S0378517317310268
The synergistic combination of PEs and lipid vesicles produces promising skin drug delivery systems. According to Chessa et al. ( Chessa et al., 2011 ), the use of PEG 400 (up to 40% in the aqueous phase) as PE provides a suitable skin deposition of the of quercetin, a lipophilic antioxidant agent, in different skin layers, mainly in the epidermis.Author: M. Sala, R. Diab, A. Elaissari, H. Fessi
https://ijpsr.com/bft-article/transdermal-drug-delivery-system-a-review/?view=fulltext
1 Transdermal Drug Delivery System (TDDS) are defined as self contained, discrete dosage forms which are also known as “patches” 2, 3 when patches are applied to the intact skin, deliver the drug through the skin at a controlled rate to the systemic circulation.
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in the near future.
https://www.3m.com/3M/en_US/drug-delivery-systems-us/
Take advantage of our more than 50 years of global pharmaceutical development and manufacturing services experience. Work hand-in-hand using proven inhalation, transdermal, oral and topical manufacturing expertise from feasibility to market -- all while ensuring the highest standards of manufactured product delivery in drug delivery systems.
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