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https://www.nature.com/articles/srep21881
Feb 24, 2016 · In conclusion, this is the first study to develop and show that receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient and safe non …Author: Yu-Wai-Man C, Tagalakis Ad, Manunta, Hart Sl, Khaw Pt
https://www.ncbi.nlm.nih.gov/pubmed/22023849
Mar 28, 2012 · Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design. Buyens K(1), De Smedt SC, Braeckmans K, Demeester J, Peeters L, van Grunsven LA, de Mollerat du Jeu X, Sawant R, …Author: Kevin Buyens, Stefaan C. De Smedt, Kevin Braeckmans, Joseph Demeester, Liesbeth Peeters, Leo A. van ...
https://www.sciencedirect.com/science/article/pii/S0378517318306185
Taken together, our results suggested the intracellular delivery efficiency of exosome-mimicking liposomes was actually improved to a greater extent by mimicking the unique lipid composition of exosomes. However, it still remained far from adequate for efficient siRNA delivery when compared with cationic liposomes.Author: Mei Lu, Xiaoyun Zhao, Haonan Xing, Zhe Xun, Shimeng Zhu, Lang Lang, Tianzhi Yang, Cuifang Cai, Dongk...
https://www.sciencedirect.com/science/article/pii/S0142961215009667
In this section we focus on the effect of the surface charge of liposome carriers involved in siRNA delivery. As discussed in Section 1, effective systemic siRNA delivery requires: (1) sufficiently long blood circulation time, (2) efficient penetration into tumor tissues, and (3) high cellular uptake and efficient endosomal escape. In the ...Author: Yuqiong Xia, Jie Tian, Jie Tian, Xiaoyuan Chen
https://www.researchgate.net/profile/Robert_Coleman5/publication/6691975_Intraperitoneal_delivery_of_liposomal_siRNA_for_therapy_of_advanced_ovarian_cancer/links/0912f50a8e6b78d902000000.pdf?disableCoverPage=true
(IP) delivery of these siRNA complexes was as effective at delivery and therapy as IV delivery. Experimental design: SiRNA was incorporated into the neutral liposome 1,2‑dioleoyl‑
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225218/
Oct 26, 2011 · Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells. Cheng-Wei Chen, 1 Da-Wen Lu, 2 Ming-Kung Yeh, 3 Chia-Yang Shiau, 4 and Chiao-Hsi Chiang 1, 5 Author information ...Author: Cheng-Wei Chen, Da-Wen Lu, Ming-Kung Yeh, Chia-Yang Shiau, Chiao-Hsi Chiang
https://www.cell.com/molecular-therapy-family/molecular-therapy/pdf/S1525-0016(16)32258-4.pdf
(RNAi) therapy to target CD47 by systemically delivering siRNA formulated in the liposome-protamine-hyaluronic acid (LPH) nanoparticles (NPs). The LPH-NP is a well-established in vivo siRNA delivery system that is optimized for systemic delivery of siRNA to …
https://www.nature.com/articles/nbt1396
Mar 30, 2008 · It is also noteworthy that our vitamin A–coupled liposome system for the delivery of siRNA appeared to be quite efficient compared with previously reported methods using conventional liposomes.Author: Yasushi Sato, Kazuyuki Murase, Junji Kato, Masayoshi Kobune, Tsutomu Sato, Yutaka Kawano, Rishu Taki...
http://altogenlabs.com/pre-clinical-research-services/liposome-encapsulation-services-sirna-mirna-dna-proteins/
Liposomes are used to efficiently deliver cargo molecules (such as siRNA, mRNA, DNA, RNA, protein) into cells in vitro and in vivo. Liposome encapsulation enables intracellular transport and delivery of pharmaceutical drugs to specific cells and/or tissue targets.
https://avantilipids.com/product/640009
siRNA Delivery Kit Lipids. Please Confirm Your Location. Effective March 1, 2018, Merck KGaA, Darmstadt, Germany* is the exclusive Distributor of Avanti Polar Lipids, Inc. Research Products for all countries except the United States.
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