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https://www.sciencedirect.com/science/article/pii/S0006291X0901314X
For RNA interference (RNAi) mediated silencing of the ABCB1 gene in Caco-2 cells biocompatible luminescent silicon quantum dots (SiQDs) were developed to serve as self-tracking transfection tool for ABCB1 siRNA. While the 2–3 nm sized SiQD core exhibits green luminescence, the QD surfaces are completely saturated with covalently linked 2-vinylpyridine that may electrostatically bind siRNA.Author: S. Klein, O. Zolk, M.F. Fromm, F. Schrödl, W. Neuhuber, C. Kryschi
https://www.researchgate.net/publication/272335057_Silicon_Quantum_Dots_Functionalized_for_siRNA_Delivery
Biocompatible, water-soluble, green luminescent silicon quantum dots (SiQDs) were developed as transfection tool for small interfering RNA (siRNA).
https://www.researchgate.net/publication/26646816_Functionalized_silicon_quantum_dots_tailored_for_targeted_siRNA_delivery
Functionalized silicon quantum dots tailored for targeted siRNA delivery Article in Biochemical and Biophysical Research Communications 387(1):164-8 · October 2009 with 52 Reads How we measure ...
https://www.ncbi.nlm.nih.gov/pubmed/19576864
Sep 11, 2009 · Functionalized silicon quantum dots tailored for targeted siRNA delivery. Klein S(1), Zolk O, Fromm MF, Schrödl F, Neuhuber W, Kryschi C. Author information: (1)Department Chemistry and Pharmacy, Physical Chemistry I and ICMM, Friedrich-Alexander University of Erlangen-Nuremberg, Egerlandstrasse 3, Erlangen, Germany.Author: S. Klein, O. Zolk, M.F. Fromm, F. Schrödl, W. Neuhuber, C. Kryschi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622398/
Gene silencing using short interfering RNA (siRNA) is becoming an attractive approach for probing gene function in mammalian cells. This study evaluated the specificity and efficiency of quantum dots (QDs) as non-viral gene vectors for delivery of survivin siRNA and downregulation of survivin gene expression in oral squamous cell carcinoma Tca8113 cells.Author: Jianjiang Zhao, Xiaoling Qiu, Zhiping Wang, Jie Pan, Jun Chen, Jiusong Han
https://link.springer.com/chapter/10.1007/978-981-10-5864-6_13
Aug 19, 2017 · Klein S, Zolk O, Fromm MF, Schrodl F, Neuhuber W, Kryschi C (2009) Functionalized silicon quantum dots tailored for targeted siRNA delivery. Bioch Biophys Res Commun 387:164–168 CrossRef Google ScholarAuthor: Miruna Silvia Stan, Cornelia Sima, Anca Dinischiotu
https://pubs.acs.org/doi/10.1021/ja800086u
We report the rational design of multifunctional nanoparticles for short-interfering RNA (siRNA) delivery and imaging based on the use of semiconductor quantum dots (QDs) and proton-absorbing polymeric coatings (proton sponges). With a balanced composition of tertiary amine and carboxylic acid groups, these nanoparticles are specifically designed to address longstanding barriers in siRNA ...Author: Maksym V. Yezhelyev, Lifeng Qi, Ruth M. O'Regan, Shuming Nie, Xiaohu Gao
https://pubs.acs.org/doi/abs/10.1021/acsnano.5b02357
Amphiphilic polyethyleneimine derivatives (amPEIs) were synthesized and used to encapsulate dozens of quantum dots (QDs). The QD–amPEI composite was ∼100 nm in hydrodynamic diameter and had the slightly positive outer surface that suited well for cellular internalization. The QD–amPEI showed very efficient QD cellular labeling with the labeled cell fluorescence intensity more than 10 ...Author: Joonhyuck Park, Junhwa Lee, Jungheon Kwag, Yeonggyeong Baek, Bumju Kim, Calvin Jinse Yoon, Seoyeon B...
http://onlinelibrary.wiley.com/doi/10.1002/adma.200306111/abstract
Intracellular Delivery of Quantum Dots for Live Cell Labeling and Organelle Tracking* A. M. Derfus. ... A new technique for reversible permeabilization of live cells for intracellular delivery of quantum dots ... Real time observation and kinetic modeling of the cellular uptake and removal of silicon quantum dots ...
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2013/Lecture%208/References/Derfus_2007.pdf
Targeted Quantum Dot Conjugates for siRNA Delivery Austin M. Derfus,†,‡ Alice A. Chen,§,3 Dal-Hee Min,§ Erkki Ruoslahti,‡,# and Sangeeta N. Bhatia*,†,§ Department of Bioengineering, University of California at San Diego, La Jolla, California 92093, Burnham Institute for Medical
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