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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943960/
Dec 25, 2017 · Mesoporous Silica Nanoparticles as Drug Delivery Systems MSNs exhibit unique characteristics that make them ideal nanocarriers to host, protect and transport drugs to the target site. It is feasible to incorporate targeting agents in the external surface of MSNs to direct them to the unhealthy tissues aimed at increasing specificity and therefore diminishing undesired side effects.Author: María Vallet-Regí, Montserrat Colilla, Isabel Izquierdo-Barba, Miguel Manzano
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201902634
Researchers are developing novel nanoparticles for both diagnostic applications using imaging technology and treatment purposes through drug delivery technologies. Among all the available nanoparticles, inorganic mesoporous silica nanoparticles are the newcomers to the field, contributing with their unique and superlative properties.Author: Miguel Manzano, Miguel Manzano, María Vallet‐Regí, María Vallet‐Regí
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Drug delivery. Porous silica based materials for drug delivery applications emerged in the late 1990's with reports of silica nanopore membranes; one major advantage of the PSi materials is that they can be tailored for continuous or triggered drug release depending on the application. The paracellular delivery of insulin across an intestinal Caco-2 cell monolayer using micro fabricated PSi particles was one of the first examples of drug delivery …
https://www.sciencedirect.com/science/article/pii/S1549963414005462
Abstract In the past decade, mesoporous silica nanoparticles (MSNs) with a large surface area and pore volume have attracted considerable attention for their application in drug delivery and biomedicine.Author: Ying Wang, Qinfu Zhao, Ning Han, Ling Bai, Jia Li, Jia Liu, Erxi Che, Liang Hu, Qiang Zhang, Tongyin...
https://www.researchgate.net/publication/335661321_Mesoporous_Silica_Nanoparticles_for_Drug_Delivery
Mesoporous silica nanoparticles have been reported as suitable drug carriers, but their successful delivery to target tissues following systemic administration remains a challenge.
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
opment of controlled release and drug delivery devices using mesoporous silica nanomaterials, the effects of these materials on cellular development and propagation, and the difference in develop- ment between normal and cancer cells with the ultimate goal of controlling the release of antitumor drugs …
https://www.sciencedirect.com/science/article/pii/S0169409X08000951
Among many structurally stable materials that have been investigated for drug delivery, silica materials with defined structures and surface properties are known to be biocompatible. Silica is often the material of choice to enable the biological use of inorganic nanoparticles , , .Author: Igor I. Slowing, Juan L. Vivero-Escoto, Chia-Wen Wu, Victor S.-Y. Lin
https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.6b00214
Functionalized Silica Nanoparticles As an Alternative Platform for Targeted Drug-Delivery of Water Insoluble DrugsAuthor: Luciane Franca de Oliveira, Karim Bouchmella, Kaliandra de Almeida Goncalves, Jefferson Bettini, Joe...
https://www.hindawi.com/journals/jnm/2017/2069685/
Folate-Functionalized Mesoporous Silica Nanoparticles as a Liver Tumor-Targeted Drug Delivery System to Improve the Antitumor Effect of Paclitaxel Xiaoyan Xu, 1 Chao Wu, 1 Andi Bai, 1 Xuan Liu, 1 Huiling Lv, 1 and Ying Liu 1Author: Xiaoyan Xu, Chao Wu, Andi Bai, Xuan Liu, Huiling Lv, Ying Liu
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