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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Drug delivery. Porous silica based materials for drug delivery applications emerged in the late 1990's with reports of silica nanopore membranes; one major advantage of the PSi materials is that they can be tailored for continuous or triggered drug release depending on the application. The paracellular delivery of insulin across an intestinal Caco-2 cell monolayer using micro fabricated PSi particles was one of the first examples of drug delivery …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943960/
Dec 25, 2017 · Mesoporous Silica Nanoparticles as Drug Delivery Systems MSNs exhibit unique characteristics that make them ideal nanocarriers to host, protect and transport drugs to the target site. It is feasible to incorporate targeting agents in the external surface of MSNs to direct them to the unhealthy tissues aimed at increasing specificity and therefore diminishing undesired side effects.Author: María Vallet-Regí, Montserrat Colilla, Isabel Izquierdo-Barba, Miguel Manzano
https://www.sciencedirect.com/science/article/pii/S1734114012709015
Silica materials used in controlled drug delivery systems are classified as xerogels and mesoporous silica nanoparticles (MSNs), e.g., MCM-41 (Mobil Composition of Matter) and SBA-15 (Santa Barbara University mesoporous silica material) .Author: Agnieszka Z. Wilczewska, Katarzyna Niemirowicz, Karolina H. Markiewicz, Halina Car
https://link.springer.com/article/10.1007/s10971-020-05280-5
Mar 16, 2020 · Many groups have already investigated the use of NiCu magnetic nanoparticles (MNPs) as mediators for magnetic fluid hyperthermia, but we were the first to report the potential of NiCu MNPs as bimodal therapeutic systems, capable of simultaneous magnetic hyperthermia (MH) and targeted drug delivery. The superparamagnetic nanoparticles have a magnetic core, which enables their …Author: Janja Stergar, Uroš Maver, Marjan Bele, Lidija Gradišnik, Matjaž Kristl, Irena Ban
https://www.researchgate.net/publication/270012985_Mesoporous_silica_Nanoparticles_as_Drug_Delivery_System
Mesoporous silica nanoparticles (MSNs) are a versatile drug delivery system that can be used for loading of different guest molecules such as peptides, proteins, anticancer agents, and genetic...
https://www.sciencedaily.com/releases/2018/03/180323104829.htm
Mar 23, 2018 · Drug delivery systems (DDSs) are important methods of delivering medicine to affected areas. An international collaborative research group has successfully developed the world's first DDS for antimalarial drugs.
https://nanoscalereslett.springeropen.com/articles/10.1186/s11671-019-3208-3
Dec 23, 2019 · We herein construct an efficient cell-targeting drug delivery system (Sgc8-MSN/Dox) based on aptamer-modified mesoporous silica nanoparticles that relies on the tumor-targeting ability of the aptamer Sgc8 to deliver doxorubicin (Dox) to leukemia cells in a targeted way, thereby improving therapeutic efficacy and reducing toxicity.Author: Yang Yang, Weihua Zhao, Wenwen Tan, Zongqiang Lai, Dong Fang, Lei Jiang, Chuantian Zuo, Nuo Yang, Yo...
https://www.hindawi.com/journals/jnm/2017/2069685/
Folate-Functionalized Mesoporous Silica Nanoparticles as a Liver Tumor-Targeted Drug Delivery System to Improve the Antitumor Effect of Paclitaxel Xiaoyan Xu, 1 Chao Wu, 1 Andi Bai, 1 Xuan Liu, 1 Huiling Lv, 1 and Ying Liu 1Author: Xiaoyan Xu, Chao Wu, Andi Bai, Xuan Liu, Huiling Lv, Ying Liu
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
opment of controlled release and drug delivery devices using mesoporous silica nanomaterials, the effects of these materials on cellular development and propagation, and the difference in develop- ment between normal and cancer cells with the ultimate goal of controlling the release of antitumor drugs in cancer cells.
https://www.sciencedirect.com/science/article/pii/S1549963414005462
In the past decade, mesoporous silica nanoparticles (MSNs) with a large surface area and pore volume have attracted considerable attention for their application in drug delivery and biomedicine.Author: Ying Wang, Qinfu Zhao, Ning Han, Ling Bai, Jia Li, Jia Liu, Erxi Che, Liang Hu, Qiang Zhang, Tongyin...
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