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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764983/
The tuneable mesopore structure and modifiable surface of mesoporous silica nanoparticle allow incorporation of various classes of drug molecules and controlled delivery to the target sites. This review aims to present the state of knowledge of currently available drug delivery system and identify properties of an ideal drug carrier for specific application, focusing on mesoporous silica nanoparticles.Author: Sooyeon Kwon, Rajendra K Singh, Roman A Perez, Ensanya A Abou Neel, Ensanya A Abou Neel, Ensanya A A...
https://pubs.rsc.org/en/content/articlelanding/2011/jm/c0jm03851b
The biomedical applications of mesoporous silica nanoparticles (MSNs) as efficient drug delivery carriers have attracted great attention in the last decade. The structure, morphology, size, and surface properties of MSNs have been found to be facilely tunable for the purposes of drug loading, controlled drug release and delivery, and multifuctionalization.Author: Qianjun He, Jianlin Shi
https://www.researchgate.net/publication/256477597_Silica-Based_Mesoporous_Nanoparticles_for_Controlled_Drug_Delivery
In particular, mesoporous silica nanoparticles are widely used as a delivery reagent because silica possesses favourable chemical properties, thermal stability and biocompatibility.
https://cyberleninka.org/article/n/642820
Academic research paper on topic "Silica-based mesoporous nanoparticles for controlled drug delivery" Article. Silica-based mesoporous nanoparticles for controlled drug delivery. Sooyeon Kwon1, Rajendra K Singh2,3, Roman A Perez3, Ensanya A Abou Neel4,5,6, Hae-Won Kim2,3,7 and Wojciech Chrzanowski1.Author: Sooyeon Kwon, Rajendra K Singh, Roman A Perez, Ensanya A Abou Neel, Ensanya A Abou Neel, Ensanya A A...
https://pubs.acs.org/doi/abs/10.1021/ja901831u
A boronic acid-functionalized mesoporous silica nanoparticle-based drug delivery system (BA-MSN) for glucose-responsive controlled release of both insulin and cyclic adenosine monophosphate (cAMP) was synthesized. Fluorescein isothiocyanate-labeled, gluconic acid-modified insulin (FITC-G-Ins) proteins were immobilized on the exterior surface of BA-MSN and also served as caps to encapsulate ...Author: Yannan Zhao, Brian G. Trewyn, Igor I. Slowing, Victor S.-Y. Lin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Drug delivery. Porous silica based materials for drug delivery applications emerged in the late 1990's with reports of silica nanopore membranes; one major advantage of the PSi materials is that they can be tailored for continuous or triggered drug release depending on the application. The paracellular delivery of insulin across an intestinal Caco-2 cell monolayer using micro fabricated PSi particles was one of the first examples of drug delivery …
https://www.sciencedirect.com/science/article/pii/S0169409X08000951
In this review, we highlight the recent research developments of a series of surface-functionalized mesoporous silica nanoparticle (MSN) materials as efficient drug delivery carriers. The synthesis of this type of MSN materials is described along with the current methods for controlling the structural properties and chemical functionalization for biotechnological and biomedical applications.Author: Igor I. Slowing, Juan L. Vivero-Escoto, Chia-Wen Wu, Victor S.-Y. Lin
https://www.sciencedirect.com/science/article/pii/S0169409X15002124
Nanoparticles that respond to internal and external stimuli to carry out controlled release of anticancer drugs have been developed. In this review, we focus on the development of mesoporous silica based nanoparticles, as this type of materials provides a relatively stable material that is amenable to various chemical modifications.Author: Harutaka Mekaru, Jie Lu, Fuyuhiko Tamanoi
https://pubs.rsc.org/en/content/articlelanding/2012/cs/c2cs15308d
This review highlights the most recent research progress on silica-based controlled drug delivery systems, including: (i) pure mesoporous silica sustained-release systems, (ii) magnetism and/or luminescence functionalized mesoporous silica systems which integrate targeting and tracking abilities of drug molecules, and (iii) stimuli-responsive ...Author: Piaoping Yang, Piaoping Yang, Shili Gai, Jun Lin
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