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https://www.ncbi.nlm.nih.gov/pubmed/19214755
Siderophores as drug delivery agents: application of the "Trojan Horse" strategy. Möllmann U(1), Heinisch L, Bauernfeind A, Köhler T, Ankel-Fuchs D. Author information: (1)Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Jena, …Author: Ute Möllmann, Lothar Heinisch, Adolf Bauernfeind, Thilo Köhler, Dorothe Ankel-Fuchs
https://www.researchgate.net/publication/24005777_Siderophores_as_drug_delivery_agents_application_of_the_Trojan_Horse_strategy
Siderophores as drug delivery agents: application of the “Trojan Horse” strategy ... Siderophores are low molecular weight iron chelators that bind to iron and are actively transported inside ...
https://www.ncbi.nlm.nih.gov/pubmed/10637361
Studies and syntheses of siderophores, microbial iron chelators, and analogs as potential drug delivery agents. Roosenberg JM 2nd(1), Lin YM, Lu Y, Miller MJ. Author information: (1)Department of Chemistry, University of Notre Dame, Notre Dame, IN 46556, USA.Author: John M. Roosenberg, Yun-Ming Lin, Yong Lu, Marvin J. Miller
https://link.springer.com/article/10.1007%2Fs10534-009-9219-2
Feb 12, 2009 · The outer membrane permeability barrier is an important resistance factor of bacterial pathogens. In combination with drug inactivating enzymes, target alteration and efflux, it can increase resistance dramatically. A strategy to overcome this membrane-mediated resistance is the misuse of bacterial transport systems. Most promising are those for iron transport. They are vital for virulence …Author: Ute Möllmann, Lothar Heinisch, Adolf Bauernfeind, Thilo Köhler, Dorothe Ankel-Fuchs
https://pubs.acs.org/doi/abs/10.1021/ar00029a003
Drug delivery systems designed to overcome antimicrobial resistance. ... Microbial Iron Chelators as Drug Delivery Agents: The Rational Design and Synthesis of Siderophore-Drug Conjugates. ChemInform 1993, 24 (37) , no-no ...Author: Marvin J. Miller, Francois Malouin
https://www.cell.com/trends/pharmacological-sciences/fulltext/S0165-6147(14)00110-2
Sep 01, 2014 · Antibiotic resistance in bacteria is a growing health problem for all the major classes of antibiotics used in the treatment of infectious diseases. One of the crucial mechanisms of antibiotic resistance in bacteria is decreased permeability of the outer membrane. One method to circumvent the resistance caused by this mechanism is to ‘smuggle’ the antibiotic molecule into the bacterial ...Author: Agnieszka Górska, Anna Sloderbach, Michał Piotr Marszałł
https://www.researchgate.net/profile/Ute_Moellmann/publication/24005777_Siderophores_as_drug_delivery_agents_application_of_the_Trojan_Horse_strategy/links/00b7d51f69cc2d5e65000000/Siderophores-as-drug-delivery-agents-application-of-the-Trojan-Horse-strategy.pdf
Siderophores as drug delivery agents: application of the ‘‘Trojan Horse’’ strategy Ute Mo¨llmann Æ Lothar Heinisch Æ Adolf Bauernfeind Æ
http://europepmc.org/abstract/MED/19214755
Sep 01, 2009 · The outer membrane permeability barrier is an important resistance factor of bacterial pathogens. In combination with drug inactivating enzymes, target alteration and efflux, it can increase resistance dramatically. A strategy to overcome this membrane-mediated resistance is the misuse of bacterial transport systems.Author: Ute Möllmann, Lothar Heinisch, Adolf Bauernfeind, Thilo Köhler, Dorothe Ankel-Fuchs
https://www.sciencedirect.com/science/article/pii/S0165614714001102
However, some of these technologies may have uses beyond simple drug delivery. The siderophore–drug strategy is an example. Because this methodology uses iron ion-chelating agents, which may be taken up into the body using active transport mechanisms, then, by analogy, these compounds may also be used to facilitate the elimination of iron ...Author: Agnieszka Górska, Anna Sloderbach, Michał Piotr Marszałł
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