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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477795/
We report the engineering of a novel lipid-polymer hybrid nanoparticle (NP) as a robust drug delivery platform, with high drug encapsulation yield, tunable and sustained drug release profile, excellent serum stability, and potential for differential targeting of cells or tissues.Author: Liangfang Zhang, Juliana M. Chan, Frank X. Gu, June Wha Rhee, Andrew Z. Wang, Andrew Z. Wang, Aleksa...
https://pubs.acs.org/doi/abs/10.1021/nn800275r
We report the engineering of a novel lipid−polymer hybrid nanoparticle (NP) as a robust drug delivery platform, with high drug encapsulation yield, tunable and sustained drug release profile, excellent serum stability, and potential for differential targeting of cells or tissues. The NP comprises three distinct functional components: (i) a hydrophobic polymeric core where poorly water ...Author: Liangfang Zhang, Juliana M. Chan, Frank X. Gu, June Wha Rhee, Andrew Z. Wang, Andrew Z. Wang, Aleksa...
https://www.ncbi.nlm.nih.gov/pubmed/19206374
We report the engineering of a novel lipid-polymer hybrid nanoparticle (NP) as a robust drug delivery platform, with high drug encapsulation yield, tunable and sustained drug release profile, excellent serum stability, and potential for differential targeting of cells or tissues.Author: Liangfang Zhang, Juliana M. Chan, Frank X. Gu, June Wha Rhee, Andrew Z. Wang, Andrew Z. Wang, Aleksa...
https://www.researchgate.net/publication/23997050_Self-Assembled_Lipid-Polymer_Hybrid_Nanoparticles_A_Robust_Drug_Delivery_Platform
We report the engineering of a novel lipid-polymer hybrid nanoparticle (NP) as a robust drug delivery platform, with high drug encapsulation yield, tunable and sustained drug release profile ...
https://www.academia.edu/14294517/Self-Assembled_Lipid_Polymer_Hybrid_Nanoparticles_A_Robust_Drug_Delivery_Platform
Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.542.3430
self-assembled lipidpolymer hybrid nanoparticles robust drug delivery platform dominant class phar-macokinetic property systemic administra-tion clinical use clinical development bio-degradable copolymer thera-peutic index large number polymeric nano-particles polymeric np drug class nanoparticle-based therapeutic product
https://www.ukessays.com/essays/chemistry/self-assembled-lipid-polymer-hybrid-nanoparticles-article-review.php
Critical Review of the Article “Self-Assembled Lipid-Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform” 1. Introduction. The primary author of this article Dr. Liangfang Zhang is currently serving as a Professor in the Department of Nanoengineering at the University of California San Diego. In UCSD the research in Dr. Zhang’s lab focuses on overcoming the therapeutic barriers ...
https://www.sciencedirect.com/science/article/pii/S0939641113002464
To address the limitations of polymeric nanoparticles and liposomes, a new generation delivery vehicle of therapeutics termed lipid–polymer hybrid nanoparticles (LPNs) has been developed .The LPNs, which combine the characteristics of both polymeric nanoparticles and liposomes, comprise three components as illustrated in Fig. 1.They are (1) a polymer core in which the therapeutic substances ...Author: Kunn Hadinoto, Ajitha Sundaresan, Wean Sin Cheow
https://www.pnas.org/content/108/27/10980
Jul 05, 2011 · The erythrocyte membrane-coated nanoparticles reported herein are structurally analogous to the commonly cited lipid-polymer hybrid nanoparticles, which are quickly emerging as a promising multifunctional drug delivery platform that contains the desirable characteristics of both liposomes and polymeric nanoparticles (27, 28). Lipid-polymer ...Author: Che Ming J Hu, Li Zhang, Santosh Aryal, Connie Cheung, Ronnie H. Fang, Liangfang Zhang
https://www.sciencedirect.com/science/article/pii/S0378517320302301
Nowadays, lipid polymer hybrid nanoparticles (LPHNs), a new category of therapeutic nanocarriers, have arrived as a promising drug delivery system to overcome the possible drawbacks and to integrate the effective features of liposomes and polymeric nanoparticles (Wakaskar, 2018, Zhang et al., 2015).
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