Self-Assembled Cationic Nanogels For Intracellular Protein Delivery

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Self-Assembled Cationic Nanogels for Intracellular Protein ...

    https://pubs.acs.org/doi/abs/10.1021/bc700422s
    Mar 13, 2008 · An effective intracellular protein delivery system with self-assembled cationic nanogels is reported. Interaction of proteins with self-assembled nanogels of cationic cholesteryl group-bearing pullulans (CHPNH2) was investigated by dynamic light scattering (DLS), transmission electron micrograph (TEM), fluorescence resonance energy transfer (FRET), and fluorescence correlation …Author: Hirohito Ayame, Nobuyuki Morimoto, Kazunari Akiyoshi

Self-Assembled Cationic Nanogels for Intracellular Protein ...

    https://pubs.acs.org/doi/10.1021/bc700422s
    An effective intracellular protein delivery system with self-assembled cationic nanogels is reported. Interaction of proteins with self-assembled nanogels of cationic cholesteryl group-bearing pullulans (CHPNH 2) was investigated by dynamic light scattering (DLS), transmission electron micrograph (TEM), fluorescence resonance energy transfer (FRET), and fluorescence correlation spectroscopy (FCS).Author: Hirohito Ayame, Nobuyuki Morimoto, Kazunari Akiyoshi

Self-Assembled Cationic Nanogels for Intracellular Protein ...

    https://www.researchgate.net/publication/5516356_Self-Assembled_Cationic_Nanogels_for_Intracellular_Protein_Delivery
    An effective intracellular protein delivery system with self-assembled cationic nanogels is reported. Interaction of proteins with self-assembled nanogels of cationic cholesteryl group-bearing ...

Charge-reversal nanoparticles: novel targeted drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951588/
    Akiyoshi et al.47 constructed an effective intracellular protein delivery system from self-assembled cationic nanogels. They investigated the interaction of proteins with self-assembled nanogels from cationic cholesteryl group-bearing pullulans (CHPNH 2). The cationic nanogels strongly interacted with bovine serum albumin (BSA) which formed ...Author: Xinli Chen, Lisha Liu, Chen Jiang

Intracellular delivery and anti-cancer effect of self ...

    https://www.sciencedirect.com/science/article/pii/S0168365910006450
    As a result, the HP nanogel with RNase A exhibited significant cytotoxicity that was dependent on the concentration of RNase A. Self-assembled heparin-Pluronic nanogels can not only be applied to the intracellular delivery of various proteins but also can be tailored …Author: Jong Hoon Choi, Ji Young Jang, Ji Young Jang, Yoon Ki Joung, Myung Hee Kwon, Ki Dong Park

Intracellular Protein Delivery Using Self-Assembled ...

    https://www.researchgate.net/publication/300705727_Intracellular_Protein_Delivery_Using_Self-Assembled_Amphiphilic_Polysaccharide_Nanogels
    Request PDF Intracellular Protein Delivery Using Self-Assembled Amphiphilic Polysaccharide Nanogels Intracellular delivery of exogenous proteins is a field of bioscience that has grown rapidly ...

Promises and Pitfalls of Intracellular Delivery of Proteins

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166028/
    Sep 17, 2014 · Introduction. Protein delivery has important applications both in vitro and in vivo.In vitro, delivery of proteins into cells provides a potentially game-changing approach to manipulate signaling pathways, 1 stimulate potent antitumor immune cells, 2 and induce pluripotency for tissue engineering and wound healing. 3 Effective in vivo protein delivery would provide therapeutic replacement of ...Author: Ailing Fu, Rui Tang, Joseph Hardie, Michelle E. Farkas, Vincent M. Rotello

Intracellular Protein Delivery Using Self-Assembled ...

    https://link.springer.com/chapter/10.1007%2F978-94-017-8896-0_14
    Ayame H, Morimoto N, Akiyoshi K (2008) Self-assembled cationic nanogels for intracellular protein delivery. Bioconjug Chem 19(4):882–890 PubMed CrossRef Google Scholar Fujioka-Kobayashi M, Ota MS, Shimoda A et al (2012) Cholesteryl group- and acryloyl group-bearing pullulan nanogel to deliver BMP2 and FGF18 for bone tissue engineering.Author: Asako Shimoda, Shin-ichi Sawada, Kazunari Akiyoshi

Current advances in self-assembled nanogel delivery ...

    https://www.sciencedirect.com/science/article/pii/S0169409X1500229X
    The DEAE group is an effective cationic group for intracellular protein delivery via nanogels consisting of enzymatically synthesized glycogen ; therefore, we evaluated CH-CA-DEAE self-nanogels for the intracellular delivery of native CpG DNA. CpG oligo-DNA induces inflammatory immune responses through cytokine production and is commonly used ...Author: Yoshiro Tahara, Kazunari Akiyoshi

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