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https://link.springer.com/article/10.1007/s11095-011-0412-y
Mar 18, 2011 · ABSTRACT. A wide range of organic and inorganic materials have been used in the development of nano-scale self-assembling gene delivery systems to improve the therapeutic efficacy of nucleic acid drugs. Small interfering RNA (siRNA) has recently been recognized as a promising and potent nucleic acid medicine for the treatment...Author: Ji Hoon Jeong, Tae Gwan Park, Sun Hwa Kim
https://www.researchgate.net/publication/50597608_Self-Assembled_and_Nanostructured_siRNA_Delivery_Systems
Request PDF Self-Assembled and Nanostructured siRNA Delivery Systems A wide range of organic and inorganic materials have been used in the development of nano-scale self-assembling …
https://www.deepdyve.com/lp/springer-journals/self-assembled-and-nanostructured-sirna-delivery-systems-lDiCL8bjMZ
Mar 18, 2011 · Self-Assembled and Nanostructured siRNA Delivery Systems Small interfering RNA (siRNA) has recently been recognized as a promising and potent nucleic acid medicine for the treatment of incurable genetic disorders including cancer; however, siRNA-based therapeutics suffer from the same delivery problems as conventional nucleic acid drugs such as plasmid DNA and antisense oligonucleotides.
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201801223
Nov 12, 2018 · To date, there is still lack of documentation on the short‐ and long‐term biosafety of nanostructured LLC systems. A myriad of in vivo investigations have mostly focused on the biopharmaceutical performances of LLC materials in terms of improved oral or topical drug pharmacokinetics; 4, 45,...Author: Angel Tan, Linda Hong, Joanne D. Du, Ben J. Boyd
https://www.sciencedirect.com/science/article/pii/S0021979716306403
Light-responsive bulk self-assembled lipid drug delivery systems. (a) Subcutaneous NIR controlled release of a model drug from a subcutaneous depot of a phytantriol-gold nanorod cubic phase. Upon laser exposure (red shading), the mesophase forms the inverse hexagonal phase nanostructure causing a slow release of drug.Author: Wye-Khay Fong, Wye-Khay Fong, Renata Negrini, Jijo J. Vallooran, Raffaele Mezzenga, Ben J. Boyd
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364503/
Feb 06, 2019 · The current understanding is that, these nanostructured nonlamellar LLC phases are developed to overcome the suboptimal performance of the commonly used micelle, emulsion, and liposome systems in terms of local and systemic tolerability, encapsulation efficiency, physical instability, manufacturing and excipient costs, and more importantly, sustained‐release control. 108, 109 …Author: Angel Tan, Linda Hong, Joanne D. Du, Ben J. Boyd
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