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http://rnai.technology/rnai-type/top-rani-gene-therapy-companies/
Top RNAi and gene therapy companies, ddRNAi, DNA vaccines RNAi Medicine, RNAi Developments, Gene Therapy, RNAi Stocks, RNAi Technology, RNAi …
https://www.nature.com/articles/nmat3765
Oct 23, 2013 · RNA interference (RNAi) has broad potential as a therapeutic to reversibly silence any gene. To achieve the clinical potential of RNAi, delivery materials are required to transport short ...
http://s1.q4cdn.com/460208960/files/Mar%2021,%202013_TKMR_Unique%20LNP%20RNAi%20delivery%20technology,%20diversified%20pipeline,%20strong%20balance%20sheet_Zeng_v001_a2su14.pdf
about the Companys lipid nanoparticle (LNP) RNAi delivery technology, which enables systemic delivery of RNAi drug candidates. RNAi is one of the most promising targeted therapies, but is challenged by its systemic delivery and distribution into diseased areas in humans. Tekmiras LNP platform technology has great potential to achieve this goal.
https://dicerna.com/our-galxc-technology/
Our proprietary GalXC technology leverages a naturally occurring biologic process, ribonucleic acid interference, RNAi, to create therapies that silence disease-causing genes. This platform enables Dicerna to create molecules that can effectively interfere with the RNAi processes that lead to defective or misregulated proteins that cause disease.
https://phiopharma.com/technology-2/self-delivering-rnai/
A successful RNAi therapeutic platform includes stable, specific and potent RNAi compounds and the ability to deliver these compounds to the tissue(s) of choice. Scientists at Phio have developed an innovative approach to delivery in which drug-like properties were built into the RNAi compound itself.
https://www.alnylam.com/our-science/
Science That Can Change the World. The discovery of RNA interference (RNAi) has been heralded as a major scientific breakthrough of the kind that happens only once every decade or so, and it represents one of the most promising and rapidly advancing frontiers in biology and drug discovery today.
https://www.thestreet.com/investing/stocks/7-firms-developing-rnai-drugs-10713267
Mar 30, 2010 · 7 Firms Developing RNAi Drugs ... delivery technology from Tekmira that allows RNAi drugs to be administered systemically. Alnylam's VSP-01 liver cancer drug uses Tekmira's RNAi delivery technology.
https://www.businesswire.com/news/home/20200304005363/en/%C2%A0Vir-Alnylam-Expand-Collaboration-Advance-RNAi-Therapeutics
Vir and Alnylam Expand Collaboration to Advance RNAi Therapeutics for the Treatment of Coronavirus Infection, Including COVID-19 — Recent Alnylam advances in lung delivery technology suggest ...
https://igtrcn.org/issues-in-rnai-delivery-and-development/
Nov 19, 2014 · Hausseker (2014) has recently written a brief review entitled “Current issues of RNAi therapeutics delivery and development” published in the Journal of Controlled Release that is a nice summary of the current state of the art in RNAi delivery in mammalian systems with specific interest in therapeutic treatments of disease in humans.
https://news.alnylam.com/rnai/articles/harnessing-power-rnaitm-pushing-through-challenges-and-setbacks
We ultimately persisted in improving our delivery technology. One experiment at a time, we evolved the technology that is being used in Alnylam’s investigational medicines today. Now, one patient at a time, positive responses are demonstrating that RNAi technology indeed has the potential to bring about a paradigm shift in medicine.
Advirna is developing innovative solutions for oligonucleotide delivery to cells ex-vivo and in-vivo. Our technology platform - self-deliverable RNAi technology (sdRNAi) allows efficient knockdown of genes in hard-to-transfect cell lines ex vivo and in vivo using RNAi interference. sdRNAi technology is based on the deep chemical modification of siRNAs and allows efficient delivery of RNAi into ...
https://www.prnewswire.com/news-releases/solstice-biologics-secures-18-million-series-a-licenses-rnai-delivery-technology-from-uc-san-diego-185639662.html
"The syndicate has provided the financial capital and strategic planning to help the founders turn their RNAi delivery technology into human therapeutics for a wide range of diseases," said George ...
https://www.genscript.com/siRNA_technology.html
GenScript vector-based siRNA technology is an adaptation of GenScript gene synthesis technology to the rise of RNA interference (RNAi) as a powerful tool for gene function analysis and drug target validation. The GenScript siRNA technology package includes siRNA design, siRNA vectors, and custom siRNA construction.
https://www.genengnews.com/news/alnylam-sues-dicerna-over-galnac-technology/
Jun 11, 2015 · Alnylam Sues Dicerna Over GalNAc Technology. ... delivery of RNAi therapeutics to hepatocytes through uptake by the asialoglycoprotein receptor. Alnylam cited a …
http://ir.arrowheadpharma.com/news-releases/news-release-details/arrowhead-research-publishes-white-paper-rnai-delivery
The technology is a radical departure from the standard liposomal or lipid nanoparticle siRNA delivery systems used by the majority of RNAi therapeutics companies. It represents one of the most promising solutions to the delivery problem that has plagued the RNAi therapeutics field since its inception.
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