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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
CONVENTIONAL OCULAR DRUG DELIVERY SYSTEMS. Topical drop instillation into the lower precorneal pocket is a patient compliant and widely recommended route of drug administration. However, most of the topically administered dose is lost due to reflux blinking and only 20% (−7 μL) of instilled dose is retained in the precorneal pocket ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
OCULAR DRUG DELIVERY SYSTEM – A REVIEW. ... techniques and novel therapeutic agents continue to provide ocular delivery systems with high therapeutic efficacy. ... design of a drug delivery ...
https://www.sciencedirect.com/science/article/pii/S0168365919302901
In addition to ocular drug delivery systems such as colloids [16,18] and polymeric implants , hydrogels are another class of material that offer favorable properties for sustained drug release . Composed of a three-dimensional network of hydrophilic polymer chains, hydrogels have …Author: Remy C. Cooper, Hu Yang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874823/
Jan 13, 2018 · Topical eye drops represent 90% of all ocular dosage forms. In recent years, medical and pharmaceutical researchers have made major advances in the field of ophthalmic administration and in ocular drug delivery systems. New ocular drug delivery systems have great potential to improve drug bioavailability in the eye.Author: Marion Dubald, Sandrine Bourgeois, Véronique Andrieu, Hatem Fessi
https://www.allfordrugs.com/ocular-drug-delivery-systems-an-overview/
12. Greaves JL and Wilson CG: Treatment of diseases of the eye with mucoadhesive delivery systems. Advance Drug Delivery Review 1993; 11: 349– 383. 13. Robinson JC: Ocular anatomy and physiology relevant to ocular drug delivery, Ophthalmic Drug Delivery Systems, New …
https://www.pharmatutor.org/articles/review-on-ocular-drug-delivery
Advantages of ocular drug delivery systems 1. Increased accurate dosing. To overcome the side effects of pulsed dosing produced by conventional systems. 2. To provide sustained and controlled drug delivery. 3. To increase the ocular bioavailability of drug by increasing the corneal contact time.
https://www.researchgate.net/publication/235924442_OCULAR_DRUG_DELIVERY_A_REVIEW
OCULAR DRUG DELIVERY: A REVIEW . Palani S *1, Nisha Mary Joseph 2, ... ocular d rug delivery systems such as eye . drops is very poor because eye is . protected by a series of complex defense.
https://www.sciencedirect.com/science/article/pii/S0024320519301195
Novel drug delivery systems have ease the instillation of eye drops and have increased patient compliance by lowering the dose of the drug. It has also targeted the sustained and controlled release property which further exacerbates and increase the ocular bioavailability by …Author: Khushwant S. Yadav, Rahul Rajpurohit, Sushmita Sharma
https://www.ijpbs.com/ijpbsadmin/upload/ijpbs_50c8546501de1.pdf
The purpose of this review is to provide an update on the current knowledge within this field of ocular drug delivery. Drug delivery to eye has always been a daunting task in the field of pharmaceutical research due to unique anatomy and physiology of the eye. One of the major problems encountered by conventional ocular dosage
https://www.tandfonline.com/doi/abs/10.3109/15569528209052130
Oct 20, 2008 · New ocular drug delivery systems are currently receiving increased attention, in part because of the expected emergence of new drugs with short biological half-lives whose usefulness may depend on a more continuous drug supply than eyedrops can provide, and also in part because of the potential of some delivery systems to reduce the side effects of the more potent drugs recently …Author: John W. Shell
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