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https://www.nejm.org/doi/full/10.1056/NEJMoa035140
Original Article from The New England Journal of Medicine — Prevention of Recurrent Preterm Delivery by 17 Alpha-Hydroxyprogesterone CaproateAuthor: Paul J. Meis, Mark Klebanoff, Elizabeth Thom, Mitchell P. Dombrowski, Baha Sibai, Atef H. Moawad, Ca...
https://www.ncbi.nlm.nih.gov/pubmed/12802023
Jun 12, 2003 · The results of several small trials have suggested that 17 alpha-hydroxyprogesterone caproate (17P) may reduce the risk of preterm delivery. METHODS: We conducted a double-blind, placebo-controlled trial involving pregnant women with a documented history of …Author: Paul J. Meis, Mark Klebanoff, Elizabeth Thom, Mitchell P. Dombrowski, Baha Sibai, Atef H. Moawad, Ca...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855838/
In one trial and one systematic review and meta-analysis , 17 alpha-hydroxyprogesterone caproate (17P) has been associated with a reduction of recurrent SPTB. It is unclear if the effects of 17P (for prior SPTB) and cerclage (for short CL) are additive in women with both risk factors.Author: Vincenzo Berghella, Dana Figueroa, Jeff M. Szychowski, John Owen, Gary D.V. Hankins, Jay D. Iams, Je...
https://www.smfm.org/publications/280-smfm-statement-use-of-17-alpha-hydroxyprogesterone-caproate-for-prevention-of-recurrent-preterm-birth
Special Delivery e-Newsletter; International Member Newsletter; ... Join. Search Search. Home » Publications & Guidelines » SMFM Statement: Use of 17-alpha hydroxyprogesterone caproate for prevention o... SMFM Statement: Use of 17-alpha hydroxyprogesterone caproate for prevention of recurrent preterm birth. Tags: preterm birth, prior preterm ...
https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.14485
Jan 31, 2017 · Objective. To compare maternal genotypes between women with and without significant prolongation of pregnancy in the setting of 17‐alpha hydroxyprogesterone caproate (17‐P) administration for the prevention of recurrent preterm birth (PTB).Author: TA Manuck, TA Manuck, TA Manuck, WS Watkins, Esplin, Esplin, J Biggio, R Bukowski, S Parry, H Zhan, ...
https://www.sciencedirect.com/science/article/pii/S0002937817302946
Study Design. This was a prospective cohort study of 17-alpha hydroxyprogesterone caproate in our obstetric population. The primary outcome was the recurrence of birth ≤35 weeks for the entire study cohort compared to a historical referent rate of 16.8% of recurrent preterm birth in our population.Author: David B. Nelson, Donald D. McIntire, Jeffrey McDonald, John Gard, Paula Turrichi, Kenneth J. Leveno
https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1111/1471-0528.14485
differences among women delivering early vs later with 17-P. Keywords 17-Alpha hydroxyprogesterone caproate, current preterm birth, pharmacogenomics, spontaneous prematurity. Tweetable abstract Several key genetic differences are present in women with recurrent preterm birth despite 17-P treatment.Author: TA Manuck, TA Manuck, TA Manuck, WS Watkins, Esplin, Esplin, J Biggio, R Bukowski, S Parry, H Zhan, ...
https://researchers.dellmed.utexas.edu/en/publications/pharmacogenomics-of-17-alpha-hydroxyprogesterone-caproate-for-rec
TY - JOUR. T1 - Pharmacogenomics of 17-alpha hydroxyprogesterone caproate for recurrent preterm birth. T2 - a case–control study. AU - the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Genomics and Proteomics Network …
https://www.sciencedirect.com/science/article/pii/S000293781400026X
458 rows · Pharmacogenomics of 17-alpha hydroxyprogesterone caproate for recurrent preterm birth …Author: Tracy Ann Manuck, Tracy Ann Manuck, W. Scott Watkins, Barry Moore, M. Sean Esplin, M. Sean Esplin, M...
https://www.sciencedirect.com/science/article/pii/S0002937807000038
Cite this article as: Rebarber A, Ferrara LA, Hanley ML, et al. Increased recurrence of preterm delivery with early cessation of 17-alpha-hydroxyprogesterone caproate. Am J Obstet Gynecol 2007;196:224.e1-224.e4. Reprints not available from the authors.
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