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https://www.nejm.org/doi/full/10.1056/NEJMoa035140
Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that 17...Author: Paul J. Meis, Mark Klebanoff, Elizabeth Thom, Mitchell P. Dombrowski, Baha Sibai, Atef H. Moawad, Ca...
https://www.ncbi.nlm.nih.gov/pubmed/12802023
Jun 12, 2003 · BACKGROUND: Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that 17 alpha-hydroxyprogesterone caproate (17P) may reduce the risk of preterm delivery.Author: Paul J. Meis, Mark Klebanoff, Elizabeth Thom, Mitchell P. Dombrowski, Baha Sibai, Atef H. Moawad, Ca...
https://www.nejm.org/doi/full/10.1056/NEJM200309113491115
To the Editor: After reading the article by Meis et al. (June 12 issue),1 we strongly discourage practitioners from using 17 alpha-hydroxyprogesterone caproate in …
https://www.smfm.org/publications/280-smfm-statement-use-of-17-alpha-hydroxyprogesterone-caproate-for-prevention-of-recurrent-preterm-birth
SMFM Statement: Use of 17-alpha hydroxyprogesterone caproate for prevention of recurrent preterm birth. Tags: preterm birth, prior preterm birth. Categories: SMFM Statement. back Publication Files & Links. Original Article; 409 12th Street, SW. Washington, DC 20024
https://www.ncbi.nlm.nih.gov/pubmed/28947068
In general, progesterone is thought to maintain pregnancy through several closely linked mechanisms: (1) promotion of uterine quiescence, (2) inhibition of pro-inflammatory cells, and (3) immunosuppressive action. 17-Alpha hydroxyprogesterone caproate is currently the only medication approved to prevent recurrent preterm birth.Author: Tracy A. Manuck
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449222/
17-alpha hydroxyprogesterone caproate (17-OHPC), a synthetic progestogen, is the first and only agent to date approved for marketing by the United States Food and Drug Administration (FDA) for prevention of recurrent preterm birth. 10 This approval stems from a trial by Meis and colleagues published in 2003. 3 Following FDA approval, the American College of Obstetricians and …Author: David B. Nelson, Donald D. McIntire, Jeffrey McDonald, John Gard, Paula Turrichi, Kenneth J. Leveno
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855838/
In one trial and one systematic review and meta-analysis , 17 alpha-hydroxyprogesterone caproate (17P) has been associated with a reduction of recurrent SPTB. It is unclear if the effects of 17P (for prior SPTB) and cerclage (for short CL) are additive in women with both risk factors.Author: Vincenzo Berghella, Dana Figueroa, Jeff M. Szychowski, John Owen, Gary D.V. Hankins, Jay D. Iams, Je...
https://www.astho.org/Maternal-and-Child-Health/17P-Fact-Sheet/
17 Alpha-hydroxyprogesterone caproate (17P) Making the Case for 17P . Nearly 500,000 1babies are born preterm in the United States each year. Preterm birth (PTB), or birth less than 37 weeks gestation, puts infants at a higher risk of death and is the leading cause of longterm - …
https://www.sciencedirect.com/science/article/pii/S0002937817302946
17-alpha Hydroxyprogesterone caproate (17 OHP-C), a synthetic progestogen, is the first and only agent to date approved for marketing by the US Food and Drug Administration (FDA) for prevention of recurrent preterm birth. 10 This approval stems from a trial by Meis and colleagues 3 published in 2003.Author: David B. Nelson, Donald D. McIntire, Jeffrey McDonald, John Gard, Paula Turrichi, Kenneth J. Leveno
https://www.researchgate.net/publication/10712383_Prevention_of_Recurrent_Preterm_Delivery_by_17_Alpha-Hydroxyprogesterone_Caproate
Prevention of Recurrent Preterm Delivery by 17 Alpha-Hydroxyprogesterone Caproate Article (PDF Available) in New England Journal of Medicine 348(24):2379-85 · July 2003 with 256 Reads
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