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https://www.slideshare.net/chiranjibi68/rectal-drug-delivery-systems
Jun 22, 2016 · CONCLUSION Rectal administration is truly explored as a potential drug delivery system particularly for drugs that are either too irritating for the gut or undergo extensive first pass metabolism. The rectal drug delivery system offer patients an option that is less invasive and the drug can be administered in unconscious and pediatric patients ...
https://www.pharmatutor.org/articles/discussion-novel-rectal-drug-delivery-systems-recent-review
· The drug causing severe nausea & vomiting, the oral administration may cause emesis,in that case rectal drug delivery system is helpful, · Irritation to stomach & small intestine associated with certain drug can be avoided, in that case rectal drug delivery system is helpful, · …
https://www.tandfonline.com/doi/abs/10.1080/10837450.2018.1484766
Dec 28, 2017 · Drug delivery via the rectum is a useful alternative route of administration to the oral route for patients who cannot swallow. Traditional rectal dosage forms have been historically used for localized treatments including delivery of laxatives, treatment of hemorrhoids and for delivery of antipyretics.Author: Trusha J. Purohit, Sara M. Hanning, Zimei Wu
https://clinicalgate.com/rectal-and-vaginal-drug-delivery/
• Rectal and vaginal routes are used for local as well as systemic drug delivery and offer some unique advantages. • Both routes have a use in systemic drug delivery when the oral route is not available. • These routes are relatively less popular because of their anogenital nature and privacy aspects.
https://www.researchgate.net/publication/313161191_RECTAL_DRUG_DELIVERY_SYSTEMS
An osmotically-powered rectal d rug delivery system, was used for the rectal infusion of the m odel drug antipyrine. The system, which is sl ightly larger than a norm al suppository ,
http://www.authorstream.com/Presentation/AJ07-983761-rectal-drug-delivery-system/
Apr 27, 2011 · REASEARCH ARTICLE (cont.) : o smotically-powered rectal drug delivery system An osmotically-powered rectal drug delivery system, was used for the rectal infusion of the model drug antipyrine. The system, which is slightly larger than a normal suppository, has a nominal pumping rate of 43 μl h − 1 over at least 30 h.
https://www.slideshare.net/KamleshWadile/rectal-drug-delivery-system
Mar 15, 2016 · Rectal Drug Delivery System 1. 1 RECTAL DRUG DELIVERY SYSTEM Presented By:- KAMLESH A. WADILE (M. Pharmacy) Department of Pharmaceutics R. C. Patel Institute of Pharmaceutical Education & Research, Shirpur.
https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/28/issue/2
Read the latest articles of Advanced Drug Delivery Reviews at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
http://globalresearchonline.net/journalcontents/v21-1/13.pdf
dosage form and drug absorption can be easily interrupted in cases of accidental overdose or suicide attempts. Drug which traditionally is only given parentally may be administered rectally. These advantages for rectal dosing require devices or formulations with specific features to give the desired drug delivery system.File Size: 359KB
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