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https://www.tandfonline.com/doi/abs/10.1080/10837450.2018.1484766
Dec 28, 2017 · Drug delivery via the rectum is a useful alternative route of administration to the oral route for patients who cannot swallow. Traditional rectal dosage forms have been historically used for localized treatments including delivery of laxatives, treatment of hemorrhoids and for delivery …Author: Trusha J. Purohit, Sara M. Hanning, Zimei Wu
http://www.authorstream.com/Presentation/AJ07-983761-rectal-drug-delivery-system/
Apr 27, 2011 · REASEARCH ARTICLE (cont.) : o smotically-powered rectal drug delivery system An osmotically-powered rectal drug delivery system, was used for the rectal infusion of the model drug antipyrine. The system, which is slightly larger than a normal suppository, has a nominal pumping rate of 43 μl h − 1 over at least 30 h.
https://clinicalgate.com/rectal-and-vaginal-drug-delivery/
Rectal drug delivery. Introduction. Anatomy and physiology of the rectum. Absorption of drugs from the rectum. Rectal dosage forms. Formulation of suppositories. Other rectal preparations. Vaginal drug delivery. Introduction. Anatomy and physiology of the vagina. Absorption of drugs from the vagina. Vaginal dosage forms. Drug-release mechanisms
https://www.slideshare.net/chiranjibi68/rectal-drug-delivery-systems
Jun 22, 2016 · CONCLUSION Rectal administration is truly explored as a potential drug delivery system particularly for drugs that are either too irritating for the gut or undergo extensive first pass metabolism. The rectal drug delivery system offer patients an option that is less invasive and the drug can be administered in unconscious and pediatric patients. Rectal drug delivery with the advantages of enhancement in drug …
https://www.pharmatutor.org/articles/discussion-novel-rectal-drug-delivery-systems-recent-review
Rectal drug delivery is an efficient alternate to oral and parenteral route of administration in partial avoidance of first pass metabolism and protein peptide drug delivery. This route allows both local and systemic therapy of drugs.
https://www.researchgate.net/publication/313161191_RECTAL_DRUG_DELIVERY_SYSTEMS
the rectal infusion of the m odel drug antipyrine. The system, which is sl ightly larger than a norm al suppository , has a nominal pum ping rate of 43 μl h− 1 over a t least 30 h.
http://globalresearchonline.net/journalcontents/v21-1/13.pdf
dosage form and drug absorption can be easily interrupted in cases of accidental overdose or suicide attempts. Drug which traditionally is only given parentally may be administered rectally. These advantages for rectal dosing require devices or formulations with specific features to give the desired drug delivery system.File Size: 359KB
https://www.powershow.com/view/3ad800-Yjk0M/buccal_drug_delivery_system_powerpoint_ppt_presentation?varnishcache=1
buccal drug delivery system – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3ad800-Yjk0M
http://www.ferromet.com.ar/files/excipients-for-rectal-and-vaginal-route_eng.pdf
Gattefossé is an independent global leader in the production of specialty lipidic excipients and lipid-based drug delivery systems. Working with healthcare industries for over a century, our expertise in oleochemistry has inspired the development of a diverse portfolio of …File Size: 886KB
https://www.nursingtimes.net/clinical-archive/neurology/rectal-drug-administration-in-adults-how-when-why-22-02-2016/
Rectal absorption results in more of the drug reaching the systemic circulation with less alteration on route. As well as being a more effective route for delivering medication, rectal administration also reduces side-effects of some drugs, such as gastric irritation, nausea and vomiting (Tortora and Derrickson, 2008).
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