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https://www.sciencedirect.com/science/article/pii/S0264410X00005028
3.2. Delivery of eukaryotic antigen expression vectors by attenuated Listeria strains. The second group of subunit vaccine delivery systems is based on the transport of eukaryotic antigen expression vectors — so-called DNA vaccines — by intracellular bacteria into the APC.Author: Ivaylo Gentschev, Guido Dietrich, Simone Spreng, Annette Kolb-Mäurer, Volker Brinkmann, Leander Grod...
https://www.researchgate.net/publication/221951151_Recombinant_attenuated_bacteria_for_the_delivery_of_subunit_vaccines
Using attenuated intracellular bacteria as carriers, we have developed two different approaches for the delivery of subunit vaccines encoding heterologous antigens.
https://www.vaccines.gov/basics/types
There are several different types of vaccines. Each type is designed to teach your immune system how to fight off certain kinds of germs — and the serious diseases they cause. When scientists create vaccines, they consider: How your immune system responds to the germ Who needs to be vaccinated against the germ The best technology or approach to create the vaccine Based on a number of these ...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/bacterial-vaccine
The use of live attenuated bacteria as carriers of recombinant genes is a new avenue in vaccination and is called recombinant vector vaccines. Until now, only experimental systems are available (Darji et al., 2000). For this purpose, attenuated or harmless commensal bacteria surface-express or secrete antigens of a pathogen and, by this, mimic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854212/
Sep 07, 2012 · For example, subunit vaccines will usually induce a predominant humoral immune response, while recombinant live vector vaccines and DNA vaccines are effective delivery systems for eliciting cell-mediated immunity (CMI) . The great potential of this strategy has been well demonstrated in the context of HIV vaccine development.Author: I.P. Nascimento, L.C.C. Leite
https://www.academia.edu/14061005/Recombinant_attenuated_bacteria_for_the_delivery_of_subunit_vaccines
Recombinant attenuated bacteria for the delivery of subunit vaccines
https://vaccine-safety-training.org/subunit-vaccines.html
Protein based subunit vaccines present an antigen to the immune system without viral particles, using a specific, isolated protein of the pathogen. A weakness of this technique is that isolated proteins, if denatured, may bind to different antibodies than the protein of the pathogen. Commonly used protein-based subunit vaccines are the following:
https://www.genscript.com/recombinant-vaccine.html
Some of the options include live attenuated vaccines, inactivated vaccines, DNA vaccines and recombinant subunit vaccines. See schematic below for an overview of the various approaches used to make a vaccine. This technical note discusses the basics of …
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