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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854212/
Sep 07, 2012 · Recombinant protein vaccines. Most of the vaccines under investigation today are based on highly purified recombinant proteins or subunits of pathogens ().The classical example of recombinant protein vaccines currently in use in humans is the vaccine against hepatitis B (Table 1) ().Hepatitis B virus (HBV) infection is a chronic liver disease occurring worldwide.Author: I.P. Nascimento, L.C.C. Leite
https://www.researchgate.net/publication/258334374_Biosafety_of_Recombinant_Adeno-associated_Virus_Vectors
Biosafety of Recombinant Adeno-associated Virus Vectors ... Interfacing gene delivery vehicles with biomaterials has the potential to play a key role in diversifying gene transfer capabilities ...
https://www.sciencedirect.com/science/article/pii/S0024320520302988
Apart from causing direct lysis to the cells, oncolytic viruses can also be genetically engineered with gene of interest and used as delivery vehicles for vaccine therapy. Upon infection and virus replication in the tumor cells, the gene of interest will be produced in larger amounts where it can exert its function.Author: Balamurugan Shanmugaraj, Lohanathan Bharathi Priya, B. Mahalakshmi, Shanmugam Subbiah, Rouh-Mei Hu, ...
https://www.researchgate.net/publication/12467817_Adeno-Associated_Viral_Vectors_as_a_Gene_Delivery_Vehicles_Review
Recombinant adeno-associated virus (rAAV) is a potent gene delivery vehicle capable of efficient transduction of transgenic DNA into cells. rAAV stays mainly as an episome in nondividing cells ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538580/
Gene transfer vectors based on recombinant adeno-associated virus (rAAV) are simple, versatile, and safe. While the conventional applications for rAAV vectors have focused on delivery of therapeutic genes, we have developed the system for delivery of vaccine antigens.Author: Philip R. Johnson, Bruce C. Schnepp, Mary J. Connell, Daniela Rohne, Suzanne Robinson, Georgia R. Kr...
https://issuu.com/gtmb/docs/vol12a/161
Gene Therapy & Molecular Biology Volume 12 Issue A. Vig et al: Recombinant adeno-associated virus as vaccine delivery vehicles of adenovirus-associated virus infection in infants and children.
http://www.nature.com/articles/gt200868
Apr 17, 2008 · Recombinant adeno-associated virus (rAAV) vectors possess a number of properties that may make them suitable for clinical gene therapy, including being based upon a …Author: Christian Mueller, Terence R. Flotte
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(19)30262-8
Sep 24, 2019 · Interfacing gene delivery vehicles with biomaterials has the potential to play a key role in diversifying gene transfer capabilities, including localized, patterned, and controlled delivery. However, strategies for modifying biomaterials to interact with delivery vectors must be redesigned whenever new delivery vehicles and applications are explored. We have developed a vector-independent ...Author: Seung Hyun Kim, Slgirim Lee, Slgirim Lee, Heehyung Lee, Mira Cho, David V. Schaffer, David V. Schaff...
https://en.wikipedia.org/wiki/AAV-2
Adeno-associated virus (AAV) is a small virus that infects humans and some other primate species. AAV is not currently known to cause disease.The virus causes a very mild immune response, lending further support to its apparent lack of pathogenicity.In many cases, AAV vectors integrate into the host cell genome, which can be important for certain applications, but can also have unwanted ...
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