Receptor-Targeted Liposome-Peptide Nanocomplexes For Sirna Delivery

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Receptor-targeted liposome-peptide nanocomplexes for siRNA ...

    https://www.sciencedirect.com/science/article/pii/S0142961211005412
    However, siRNA delivery in vivo remains challenging and there is therefore, a need to better understand, characterize and improve siRNA vector formulations. We have previously described the use of Receptor-Targeted Nanocomplexes (RTNs) for pDNA delivery , , , , , , . The RTN formulations in those studies consisted of one of various cationic ...Author: Aristides D. Tagalakis, Lin He, Luisa Saraiva, Kenth T. Gustafsson, Stephen L. Hart

Receptor-targeted liposome-peptide nanocomplexes for siRNA ...

    https://www.researchgate.net/publication/51176734_Receptor-targeted_liposome-peptide_nanocomplexes_for_siRNA_delivery
    In conclusion, this is the first study to develop and show that receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient and safe non-viral siRNA delivery system that could be ...

Receptor-targeted liposome-peptide-siRNA nanoparticles ...

    https://www.nature.com/articles/srep21881
    Feb 24, 2016 · In conclusion, this is the first study to develop and show that receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient and safe non …Author: Yu-Wai-Man C, Tagalakis Ad, Manunta, Hart Sl, Khaw Pt

Receptor-targeted liposome-peptide-siRNA nanoparticles ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764806/
    Biophysical properties of the liposome-peptide-siRNA nanoparticles. Figure 1 is a schematic diagram of a receptor-targeted liposome-peptide-siRNA nanoparticle prepared at a weight ratio of 1 (liposome): 4 (peptide): 1 (siRNA). All nanoparticles were strongly cationic ( + 42 to + 56 mV), with sizes around 100 nm and polydispersity indices (PDIs) less than 0.35.Author: Yu-Wai-Man C, Tagalakis Ad, Manunta, Hart Sl, Khaw Pt

Receptor-targeted liposome-peptide nanocomplexes for siRNA ...

    https://www.deepdyve.com/lp/elsevier/receptor-targeted-liposome-peptide-nanocomplexes-for-sirna-delivery-0hjb8wKCIo
    Sep 01, 2011 · Read "Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery, Biomaterials" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

A method for concentrating lipid peptide DNA and siRNA ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388080/
    Concentration experiments by reverse dialysis. The dialysis tubing was boiled in a solution of 2% NaHCO 3 /1 mM ethylenediaminetetraacetic acid (EDTA) for 10 minutes. It was then rinsed thoroughly with ddH 2 O and then boiled for 10 minutes in a solution of 1 mM EDTA. It was then rinsed with ddH 2 O, cooled at room temperature, and then stored at 4°C in a fresh solution of 1 mM EDTA.Author: Aristides D Tagalakis, Sara Castellaro, Haiyan Zhou, Alison Bienemann, Mustafa M Munye, David McCart...

Delivery of ENaC siRNA to epithelial cells mediated by a ...

    https://www.nature.com/articles/s41598-017-00662-2
    Apr 06, 2017 · Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient and safe non-viral siRNA delivery system that could be used to modulate sodium hyperabsorption, thus …Author: Maria D. I. Manunta, Aristides D. Tagalakis, Martin Attwood, Ahmad M. Aldossary, Josephine L. Barnes...

Receptor-targeted liposome-peptide-siRNA nanoparticles ...

    https://www.researchgate.net/publication/295856525_Receptor-targeted_liposome-peptide-siRNA_nanoparticles_represent_an_efficient_delivery_system_for_MRTF_silencing_in_conjunctival_fibrosis
    PDF There is increasing evidence that the Myocardin-related transcription factor/Serum response factor (MRTF/SRF) pathway plays a key role in... Find, read and cite all the research you need ...

Receptor-targeted liposome-peptide nanocomplexes for siRNA ...

    http://core.ac.uk/display/1875597
    Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery . By AD Tagalakis, L He, L Saraiva, KT Gustafsson and SL Hart. Abstract. RNA interference induced by double-stranded, small interfering RNA (siRNA) molecules has attracted great attention as a genetic therapeutic approach. Despite major advances in this field, new nanoparticle ...

Development of Targeted siRNA Nanocomplexes to Prevent ...

    https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(18)30445-3
    Sep 10, 2018 · Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis. Sci. Rep. 2016; 6: 21881. ... we have shown that peptide Y mediates the targeted delivery of siRNA in nanocomplexes to different tissues, including cells of neuronal origin, 41. Tagalakis A.D. He L. Saraiva L.Author: Owen Fernando, Aristides D. Tagalakis, Sahar Awwad, Sahar Awwad, Steve Brocchini, Steve Brocchini, P...

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