Receptor-Specific Delivery Of Liposomes Via Folate-Peg-Chol

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Receptor-Specific Delivery of Liposomes Via Folate-Peg-Chol

    https://www.tandfonline.com/doi/abs/10.3109/08982100009029385
    Oct 08, 2008 · Liposomes composed of DSPC/Chol/PEG-DSPE/folate-PEG-Chol (60/ 34/5/1, m/m) were taken up by cultured folate receptor-bearing KB cells via a saturable mechanism. Cellular binding of these liposomes could be competitively inhibited by free folic acid with an IC 50 of 0.39 mM, indicating an extraordinarily high binding affinity.Author: Wenjin Guo, Tina Lee, Jennifer Sudimack, Robert J. Lee

Receptor-Targeted Delivery of Liposomes via Folate-PEG-Chol

    https://www.researchgate.net/publication/240313416_Receptor-Targeted_Delivery_of_Liposomes_via_Folate-PEG-Chol
    Liposomes composed of DSPC/Chol/PEG-DSPE/folate-PEG-Chol (60/ 34/5/1, m/m) were taken up by cultured folate receptor-bearing KB cells via a saturable mechanism. Cellular binding of these liposomes...

Synthesis and Evaluation of A Novel Ligand for Folate ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424191/
    May 22, 2008 · Receptor-specific delivery of liposomes via folate-PEG-Chol. J Liposome Res. 2000; 10 :179–195. Haran G, Cohen R, Bar LK, Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases.Author: Guangya Xiang, Jun Wu, Yanhui Lu, Zhilan Liu, Robert J. Lee

Delivery of liposomes into cultured KB cells via folate ...

    http://www.jbc.org/content/269/5/3198.short
    Feb 04, 1994 · Following binding, cell-associated folate-PEG liposomes were internalized by folate-receptor-mediated endocytosis at 37 degrees C but not at 4 degrees C. These folate-PEG liposomes show potential for delivering large quantities of low molecular weight compounds nondestructively into folate receptor-bearing cells.

(PDF) Folate Receptor-Mediated Liposomal Delivery of a ...

    https://www.researchgate.net/publication/11042169_Folate_Receptor-Mediated_Liposomal_Delivery_of_a_Lipophilic_Boron_Agent_to_Tumor_Cells_in_Vitro_for_Neutron_Capture_Therapy
    FR-targeted liposomes incorporating the lipophilic boron agent, K [nido-7-CH3 (CH2)15-7,8-C2B9H11], into its bilayer were capable of specific receptor binding and receptor-mediated endocytosis in cultured KB cells. Such liposomes warrant further investigations for use in neutron capture therapy.

Tumor-selective targeted delivery of genes and antisense ...

    https://www.sciencedirect.com/science/article/pii/S0169409X04000213
    Tumor-selective targeted delivery of genes and antisense oligodeoxyribonucleotides via the folate receptor. Author links open overlay panel ... showed that both folate-PEG–DSPE and folate-PEG–Chol, when combined with a cationic lipid ... R.G. LeeReceptor-specific delivery of liposomes via folate-PEG–Chol. J. Liposome Res., 10 (2000), pp ...Author: Xiaobin B. Zhao, Robert J. Lee

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