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https://pubs.acs.org/doi/full/10.1021/nl102172j
Rapid Cytosolic Delivery of Luminescent Nanocrystals in Live Cells with Endosome-Disrupting Polymer ColloidsAuthor: Andrea R. Bayles, Harvind S. Chahal, Dev S. Chahal, Cheryl P. Goldbeck, Bruce E. Cohen, Brett A. Hel...
https://pubs.acs.org/doi/abs/10.1021/nl102172j
Luminescent nanocrystals hold great potential for bioimaging because of their exceptional optical properties, but their use in live cells has been limited. When nanocrystals enter live cells, they are taken up in vesicles. This vesicular sequestration is persistent and precludes nanocrystals from reaching intracellular targets. Here, we describe a unique, cationic core−shell polymer colloid ...Author: Andrea R. Bayles, Harvind S. Chahal, Dev S. Chahal, Cheryl P. Goldbeck, Bruce E. Cohen, Brett A. Hel...
https://www2.lbl.gov/tt/publications/2849pub.pdf
Rapid Cytosolic Delivery of Luminescent Nanocrystals in Live Cells with Endosome-Disrupting Polymer Colloids Andrea R. Bayles, Harvind S. Chahal, Dev S. Chahal, Cheryl P. Goldbeck, Bruce E. Cohen, and Brett A. Helms* The Molecular Foundry, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720
https://www.ncbi.nlm.nih.gov/pubmed/20831181
Oct 13, 2010 · Rapid cytosolic delivery of luminescent nanocrystals in live cells with endosome-disrupting polymer colloids. Bayles AR(1), Chahal HS, Chahal DS, Goldbeck CP, Cohen BE, Helms BA. Author information: (1)The Molecular Foundry, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.Author: Andrea R. Bayles, Harvind S. Chahal, Dev S. Chahal, Cheryl P. Goldbeck, Bruce E. Cohen, Brett A. Hel...
https://www.researchgate.net/publication/46217685_Rapid_Cytosolic_Delivery_of_Luminescent_Nanocrystals_in_Live_Cells_with_Endosome-Disrupting_Polymer_Colloids
Rapid Cytosolic Delivery of Luminescent Nanocrystals in Live Cells with Endosome-Disrupting Polymer Colloids
https://pubs.acs.org/doi/abs/10.1021/bm801199z
Here we tested the efficacy of this system for cytosolic delivery of a broad range of macromolecular cargos, and demonstrate the delivery of proteins, whole viral particles, or siRNA oligonucleotides into the cytosol of dendritic cells and epithelial cells via core−shell particles.Author: Yuhua Hu, Prabhani U. Atukorale, James J. Lu, James J. Moon, Soong Ho Um, Eun Chol Cho, Yana Wang, J...
https://pubs.acs.org/doi/10.1021/bc800089r
Rapid Cytosolic Delivery of Luminescent Nanocrystals in Live Cells with Endosome-Disrupting Polymer Colloids. Nano Letters 2010, 10 (10) , 4086-4092. DOI: 10.1021/nl102172j. Chunsoo Kim, Yuhan Lee, Jee Seon Kim, Ji Hoon Jeong, and Tae Gwan Park .Author: Igor L. Medintz, Thomas Pons, James B. Delehanty, Kimihiro Susumu, Florence M. Brunel, Philip E. Daw...
https://pubs.acs.org/doi/10.1021/la049156t
Rapid Cytosolic Delivery of Luminescent Nanocrystals in Live Cells with Endosome-Disrupting Polymer Colloids. Nano Letters 2010, 10 (10) , 4086-4092. DOI: 10.1021/nl102172j. Shaun C. Howard, V. S. J. Craig, Paul A. FitzGerald, and Erica J. Wanless . Swelling and Collapse of an Adsorbed pH-Responsive Film-Forming Microgel Measured by Optical ...Author: J. I. Amalvy, E. J. Wanless, Y. Li, V. Michailidou, S. P. Armes, Y. Duccini
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894870/
Jun 27, 2017 · While intracellular delivery of functional proteins offers tremendous therapeutic potential, 28,29 the difficulty of rapid cytosolic delivery of proteins in active conformation is massive and still represents an unmet challenge. 30,31Author: Berta Esteban-Fernández de Ávila, Doris E. Ramírez-Herrera, Susana Campuzano, Pavimol Angsantikul, L...
https://onlinelibrary.wiley.com/doi/full/10.1002/mabi.201700022
The highly reductive cytosolic environment allowed cytosolic release of the pDNA from the carrier therefore enhancing nuclear NFkB binding and nuclear targeting. 181. The nuclear delivery strategies that have been discussed so far all involve cellular internalization of the polymer nanomedicines via clathrin‐mediated endocytosis.Author: Claudia Battistella, Harm‐Anton Klok
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