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https://www.ncbi.nlm.nih.gov/pubmed/12351602
Oct 01, 2002 · 1. J Clin Oncol. 2002 Oct 1;20(19):4040-9. Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival.Author: Thomas J. Smith, Peter S. Staats, Timothy Deer, Lisa J. Stearns, Richard L. Rauck, Richard L. Boortz...
https://ascopubs.org/doi/full/10.1200/jco.2003.99.003
Sep 21, 2016 · To the Editor: The article by Dr Thomas Smith and colleagues 1 about an implantable drug delivery system compared with comprehensive medical management for refractory pain is a well-written, well-conducted, and well-analyzed industry-sponsored study. However, we have several concerns. The authors did not clearly define refractory cancer pain. The need for 200 mg or more of …Author: Mellar P. Davis, Declan Walsh, Ruth Lagman, Susan B. LeGrand
https://ascopubs.org/doi/10.1200/JCO.2002.02.118
PURPOSE: Implantable intrathecal drug delivery systems (IDDSs) have been used to manage refractory cancer pain, but there are no randomized clinical trial (RCT) data comparing them with comprehensive medical management (CMM). PATIENTS AND METHODS: We enrolled 202 patients on an RCT of CMM versus IDDS plus CMM.Author: Thomas J. Smith, Peter S. Staats, Timothy Deer, Lisa J. Stearns, Richard L. Rauck, Richard L. Boortz...
https://www.ncbi.nlm.nih.gov/pubmed/12860959
Jul 15, 2003 · 1. J Clin Oncol. 2003 Jul 15;21(14):2801-2; author reply 2802-3. Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival.Author: Thomas J. Smith, Peter S. Staats, Timothy Deer, Lisa J. Stearns, Richard L. Rauck, Richard L. Boortz...
https://www.researchgate.net/publication/10661435_Randomized_clinical_trial_of_an_implantable_drug_delivery_system
Randomized clinical trial of an implantable drug delivery system Article (PDF Available) in Journal of Clinical Oncology 21(14):2800-1; author reply 2802-3 · August 2003 with 82 Reads
https://www.medtronic.com/us-en/healthcare-professionals/therapies-procedures/neurological/targeted-drug-delivery/clinical-outcomes/cancer-pain.html
Smith TJ, Staats PS, Deer T, et al. Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival. J Clin Oncol. 2002;20(19):4040-4049.Phone: (800) 707-0933
https://jhu.pure.elsevier.com/en/publications/randomized-clinical-trial-of-an-implantable-drug-delivery-system--5
Oct 01, 2002 · Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: Impact on pain, drug-related toxicity, and survival. Journal of Clinical Oncology , 20 (19), 4040-4049.Author: Thomas J. Smith, Peter S. Staats, Timothy Deer, Lisa J. Stearns, Richard L. Rauck, Richard L. Boortz...
https://www.researchgate.net/publication/11104766_Randomized_Clinical_Trial_of_an_Implantable_Drug_Delivery_System_Compared_With_Comprehensive_Medical_Management_for_Refractory_Cancer_Pain_Impact_on_Pain_Drug-Related_Toxicity_and_Survival
Randomized Clinical Trial of an Implantable Drug Delivery System Compared With Comprehensive Medical Management for Refractory Cancer Pain: Impact on Pain, Drug-Related Toxicity, and Survival
https://www.liebertpub.com/doi/abs/10.1089/jpm.2005.8.736
Aug 29, 2005 · Background: A randomized clinical trial of implantable drug delivery system (IDDS) plus comprehensive medical management (CMM) versus CMM alone in 200 patients with refractory cancer pain showed better clinical success with IDDS. The objective of this study was to evaluate whether IDDS could help the most refractory patients failed by expert CMM.Author: Thomas J. Smith, Patrick J. Coyne
https://www.medtronic.com/us-en/healthcare-professionals/therapies-procedures/neurological/targeted-drug-delivery/education-training/about-the-therapy.html
Smith TJ, Staats PS, Deer T, et al. Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival. J Clin Oncol. 2002;20:4040-4049.Phone: (800) 707-0933
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