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https://www.bbb.org/us/ky/winchester/profile/apartments/prim1-llc-0392-9114894
PRIM1 LLC. Apartments. Business Profile. PRIM1 LLC. 200 Hubbard Rd. Winchester, KY 40391-3218 (859) 744-6366. Contact Information. 200 Hubbard …
https://www.prime1studio.com/
Prime 1 Studio is a specialty manufacturer of licensed and proprietary collectible products. The company holds various licenses for a variety of top-rated pop culture icons, including characters from Transformers, Teenage Mutant Ninja Turtles, Dc Comics, The Witcher, and many more. Prime 1 is a visual effects company which we manufacture and sale high quality figures of …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154763/
Therefore, PRIM1-depleted (Figure 2 A), mock-, and nontransfected cells (NTC) were treated with the selective ATR inhibitors AZD6738 or VE-822 , . PRIM1 depletion significantly increased the sensitivity of DLD-1 cells to treatment with ATR inhibitors (IC 50 ratios 14 and 9, respectively; Figure 2 B).
https://www.sciencedirect.com/science/article/pii/S1476558618303853
As PRIM1 inactivation sensitizes cancer cells to ATR and CHK1 inhibitors, mutations in PRIM1 or other components of the polymerase α-primase complex could represent novel targets for individualized tumor therapeutic approaches using ATR/CHK1 inhibitors, as has been previously demonstrated for POLD1, the catalytic subunit of polymerase δ.
https://www.uniprot.org/uniprot/P49642
Component of the alpha DNA polymerase complex (also known as the alpha DNA polymerase-primase complex) consisting of four subunits: the catalytic subunit POLA1, the regulatory subunit POLA2, and the primase complex subunits PRIM1 and PRIM2 respectively (PubMed: 9705292, PubMed: 26975377, PubMed: 24043831 ). Within the complex, POLA1 directly ...
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