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https://www.pdr.net/drug-summary/Precedex-dexmedetomidine-hydrochloride-1271#:~:text=Dexmedetomidine%204%20mcg%2FmL%20in%200.9%25%20Sodium%20Chloride%20Injection,2%20degrees%20C%20are%20stable%20for%2048%20hours.
https://pubmed.ncbi.nlm.nih.gov/29216621/
The stability of dexmedetomidine admixtures has previously been tested for 48 hours. The purpose of this analysis was to test the stability of dexmedetomidine admixtures for 14 days. Six dexmedetomidine admixtures of 200 mcg/50 mL were compounded in polyvinyl chloride and non-polyvinyl chloride bags, three of which were stored under refrigeration and three of which were …
https://globalrph.com/dilution/precedex-dexmedetomidine/
Stability / Miscellaneous: EXP: 24 hours (RT/REF). May be given undiluted by IV bolus. INDICATIONS AND USAGE Precedex is a relatively selective alpha2-adrenergic agonist indicated for:-Sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting.
https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=548a88c0-afda-427e-75ac-5af0cfa2224c&name=548a88c0-afda-427e-75ac-5af0cfa2224c
Precedex is not indicated for infusions lasting longer than 24 hours. Precedex should be administered using a controlled infusion device. 2.2 Dosage Information Table 1: Dosage Information ... withdraw 2 mL of Precedex Injection, and add to 48 mL of 0.9% sodium chloride injection to a total of 50 mL. Shake gently to mix well. Precedex in 0.9% ...
https://www.pdr.net/drug-summary/Precedex-dexmedetomidine-hydrochloride-1271
Prior to use, diluted dexmedetomidine admixed from a multi-dose vial may be stored for up to 4 hours at room temperature or up to 24 hours at 2 to 8 degrees C. Dexmedetomidine 4 mcg/mL in 0.9% Sodium Chloride Injection is stable for at least 48 hours at room temperature (20 to 25 degrees C) and at least 14 days refrigerated (5 degrees C) when stored in polypropylene syringes.
https://pubmed.ncbi.nlm.nih.gov/22441792/
Stability of dexmedetomidine 4 μg/mL in polypropylene syringes. Dexmedetomidine diluted to 4 μg/mL in 0.9% sodium chloride injection was stable for at least 48 hours at 20-25 °C and 14 days at 5 °C when stored in polypropylene syringes.
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