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http://www.iosrphr.org/papers/v2i2/ZL022338339.pdf
There is a constant need for new delivery systems that can provide increased therapeutic benefits to the patients. Pulsatile drug delivery is one such system (pulsincap) that, by delivering drug at the right time, right place, and in right amounts, holds
https://www.ijpsonline.com/articles/development-of-modified-pulsincap-drug-delivery-system-of-metronidazole-for-drug-targeting.html
All the formulations were assayed to determine drug content and the ability of the modified Pulsincap to provide colon-specific drug delivery was assessed by in vitro drug release studies in buffer pH 1.2 for 2 h, pH 7.4 (simulated intestinal fluid) for 3 h and pH 6.8 (stimulated colonic fluid) for 7 h.Author: Sindhu Abraham, Srinath
http://ijpsr.com/?action=download_pdf&postid=40824
DEVELOPMENT AND EVALUATION OF CHRONOMODULATED PULSINCAP DRUG DELIVERY SYSTEM OF KETOPROFEN Preetha Mathew* and Bidhu Meri Jacob Nazareth College of Pharmacy, Othera, Thiruvalla - 689546, Kerala, India. ABSTRACT: Chronotherapeutic drug delivery systems have been recognized as potentially beneficial to the chrono-therapy (time optimized)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548250/
Jul 01, 2011 · In other words, they require pulsatile drug delivery system (PDDS). The pulsatile system is gaining a lot of interest, as the drug is released completely after defined lag time (Fig. 1). Pulsatile drug delivery is time and site-specific drug delivery, thus providing spatial and temporal delivery and increasing patient compliance.Author: Deepika Jain, Richa Raturi, Vikas Jain, Praveen Bansal, Ranjit Singh
https://innovareacademics.in/journal/ijpps/Vol6Issue5/7840.pdf
Formulation of pulsatile (modified pulsincap) drug delivery system: Preparation of modified pulsincap Equivalent to 10 mg drug granules were filled in the capsule bodies and plugged with hydrogel plug. The treated body and the cap of the capsules were sealed with a …
http://www.pharmtech.com/developing-modified-pulsincap-system
Nov 01, 2009 · This therapeutic effect is prolonged by continuously releasing the medication over an extended period of time after administering a single dose. The study objective was to explore the time-and pHdependent controlled drug delivery of DS using …
https://www.researchgate.net/publication/326535280_Formulation_and_Evaluation_of_Valsartan_Pulsincap_Drug_Delivery_System_for_Treatment_of_Hypertension
Pulsincap drug delivery system of Tramadol HCL is better option for these patients and also to impart the novelty to the existing formulation. In this type of drug delivery system, delayed release ...
https://www.youtube.com/watch?v=MmGCJEqZkOY
Sep 09, 2009 · Intecs Accordion Pill™, a polymeric platform composed of materials, compliant with the FDA Inactive Ingredients Guide (IIG). The dosage form is folded in an accordion-like shape into a standard ...Author: shayosef
https://www.sciencedirect.com/science/article/pii/S0378517302000121
In spite of these reservations, the data obtained from the study in human volunteers demonstrate that the Pulsincap™ delivery system has a role as a convenient probe device and is capable of providing time-delayed release of drug substance within the GI tract.Author: Howard N.E Stevens, Clive G Wilson, Peter G Welling, Massoud Bakhshaee, Julie S Binns, Alan C Perkin...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465138/
Design and evaluation of colon targeted modified pulsincap delivery of 5-fluorouracil according to circadian rhythm. ... drug delivery system, the n value of 0.45 is indicative of Fickian diffusion controlled drug release, n value between 0 ... Srinath MS. Development of modified pulsincap drug delivery system for drug targeting. Indian J ...
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