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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548250/
Jul 01, 2011 · Pulsatile drug delivery is defined as the rapid and transient release of certain amount of molecules within a short time period immediately after a predetermined off-released period, i.e., lag time, or these systems have a peculiar mechanism of delivering the drug rapidly and completely after a lag time, i.e., a period of no drug release.Author: Deepika Jain, Richa Raturi, Vikas Jain, Praveen Bansal, Ranjit Singh
https://www.pharmatutor.org/articles/pulsatile-drug-delivery-system-a-review
Pulsatile Drug Delivery Systems are gaining a lot of interest as they deliver the drug at the right place at the right time and in the right amount, thus providing spatial and temporal delivery and increasing patient compliance. These systems are designed according to the circadian rhythm of the body.
https://www.ijpsonline.com/articles/pulsatile-drug-delivery-systems-an-approach-for-controlled-drug-delivery.pdf
Pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery …Author: Shweta Arora, J Ali, Alka Ahuja, Sanjula Baboota, J Qureshi
https://www.pharmatutor.org/articles/review-pulsatile-drug-delivery-system
Pulsatile system gaining a lot of interest as it is increasing patient compliance by means of providing time- and site-specific drug delivery system, thus providing special and temporal delivery. Pulsed or pulsatile drug release is defined as the rapid and transient release of a certain amount of drug molecules within a short time-period immediately after a predetermined off-release period.
https://www.sciencedirect.com/science/article/abs/pii/0169409X93900283
Pulsatile drug release has the advantages of avoiding drug tolerance or matching the body's release of specific peptides or hormones. In this review, recent studies for pulsatile drug delivery in response to stimuli such as chemical agents, pH, electric fields, and temperature are discussed.Author: Ryo Yoshida, Kiyotaka Sakai, Teruo Okano, Yasuhisa Sakurai
http://www.authorstream.com/Presentation/DHIREN333-1553071-pulsatile-drug-delivery/
Sep 30, 2012 · PULSATILE DRUG DELIVERY SYSTEM Pulsatile drug delivery system is defined as the rapid and transient release of certain amount of drug molecules within a short time period immediately after a predetermined off-release period, i.e., lag time.
https://www.sciencedirect.com/science/article/pii/0169409X93900283
Pulsatile drug release has the advantages of avoiding drug tolerance or matching the body's release of specific peptides or hormones. In this review, recent studies for pulsatile drug delivery in response to stimuli such as chemical agents, pH, electric fields, and temperature are discussed.Author: Ryo Yoshida, Kiyotaka Sakai, Teruo Okano, Yasuhisa Sakurai
https://www.slideshare.net/optimpharma/pulsatile-drug-delivery-system
Mar 01, 2012 · Pulsatile drug delivery system is defined as the rapid and transient release of certain amount of drug molecules within a short time period immediately after a predetermined off- release period, i.e., lag time.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065132/
Apr 14, 2014 · Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, primarily used for the treatment of hypertension, congestive heart failure, and heart attack. It belongs to BCS class III having a half-life of 12 hrs and 25% bioavailability. The purpose of the present work was to develop a press-coated, floating-pulsatile drug delivery system.
https://www.researchgate.net/publication/267829648_Pulsatile_Drug_Delivery_System_An_Overview
Conclusion: Pulsatile drug delivery system is capable of delivering the drug when and where it is required. Drug is released as a burst after a lag time (during peak morning hours) giving relief ...
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