We have collected information about Ptd/Cpp Peptide-Mediated Delivery Of Sirnas for you. Follow the links to find out details on Ptd/Cpp Peptide-Mediated Delivery Of Sirnas.
https://www.ncbi.nlm.nih.gov/pubmed/23140460
Peptide Transduction Domains (PTDs), also called Cell Penetrating Peptides (CPPs), are delivery peptides with the potential to deliver macromolecular peptides, proteins and siRNAs into cells. Here we discuss the multitude of ways that PTDs/CPPs have been utilized to deliver siRNAs from direct conjugates to complex nanoparticles.Author: Asaf Presente, Steven F. Dowdy
http://www.eurekaselect.com/108488/article
Abstract:siRNA-induced RNA Interference (RNAi) responses have great potential to treat human disease; however, siRNAs are highly charged macromolecules with no ability to enter cells and require a delivery agent. Peptide Transduction Domains (PTDs), also called Cell Penetrating Peptides (CPPs), are delivery peptides with the potential to deliver macromolecular peptides, proteins and siRNAs …
https://www.researchgate.net/publication/233392688_PTDCPP_peptide-mediated_delivery_of_siRNAs
Peptide Transduction Domains (PTDs), also called Cell Penetrating Peptides (CPPs), are delivery peptides with the potential to deliver macromolecular peptides, proteins and siRNAs into cells. Here...
https://www.tandfonline.com/doi/abs/10.1517/17425247.2015.1046431
Introduction: Macromolecular therapeutics, including enzymes, transcription factors, siRNAs, peptides and large synthetic molecules, can potentially be used to treat human diseases by targeting intracellular molecular pathways and modulating biological responses. However, large macromolecules have no ability to enter cells and require delivery vehicles.Author: Peter Lönn, Steven F Dowdy
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073348
Optimization of 599 peptide-mediated delivery of siRNAs into oral cancer cells. ( A ) Fluorescence microscopy analysis of CAL 27 oral cancer cells incubated for 2 hours with DY547-conjugated siRNA targeting CIP2A (D-siCIP2A; red) alone or in complex with increasing amounts of 599 peptide (ranging from 1 to 50-fold molar excess of siRNAs).Author: Liliana Cantini, Christopher C. Attaway, Betsy Butler, Lourdes M. Andino, Melissa L. Sokolosky, Andr...
https://www.researchgate.net/publication/277024322_Cationic_PTDCPP-mediated_macromolecular_delivery_Charging_into_the_cell
Protein transduction domains (PTDs), also known as cell-penetrating peptides (CPPs), are a diverse class of peptides that can deliver macromolecules into cells. Areas covered: In this review, we cover the uptake and usage of arginine-rich PTDs/CPPs (TAT-PTD,...
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