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https://www.ncbi.nlm.nih.gov/pubmed/24772414
In this paper, we review the most significant advancements in protein nanoparticle technology and their use in drug delivery arena. We then examine the various sources of protein materials that have been used successfully for the construction of protein nanoparticles as well as their methods of preparation.Author: Warangkana Lohcharoenkal, Liying Wang, Yi Charlie Chen, Yon Rojanasakul
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977416/
Mar 20, 2014 · Nanoparticles have increasingly been used for a variety of applications, most notably for the delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery systems have been developed for cancer treatment and various materials have been explored as drug delivery agents to improve the therapeutic efficacy and safety of anticancer drugs.Author: Warangkana Lohcharoenkal, Liying Wang, Yi Charlie Chen, Yon Rojanasakul
https://pubs.acs.org/doi/10.1021/acsbiomaterials.8b01098
This enables targeted delivery to the desired tissue and organ, which further reduces systemic toxicity. The use of protein nanoparticles for such applications could therefore prove to be a better alternative to maneuver and improve the pharmacokinetic and pharmacodynamic …Author: Annish Jain, Sumit K. Singh, Shailendra K. Arya, Subhas C. Kundu, Sonia Kapoor, Sonia Kapoor
https://www.sciencedirect.com/science/article/pii/S0958166913007222
Caged protein nanoparticles possess many desirable features for drug delivery, such as ideal sizes for endocytosis, non-toxic biodegradability, and the ability to functionalize at three distinct interfaces (external, internal, and inter-subunit) using the tools of protein engineering.Author: Nicholas M Molino, Szu-Wen Wang
https://www.researchgate.net/publication/304814091_Synthesis_of_protein_nanoparticles_for_drug_delivery
Among them, drug delivery system based on protein nanoparticles has been widely studied aiming to overcome deficiency of drug-loaded materials, such as low biocompatibility, inefficient ...
https://link.springer.com/content/pdf/10.1208%2Fs12249-019-1325-z.pdf
Nanoparticles: Oral Delivery for Protein and Peptide Drugs ... Table I. Advantages of Nanoparticles as Protein and Peptide Drug Carriers (1) 1. Reduces the enzymolysis and aggregation of protein and peptide drugs in the gastrointestinal environment and increases the transmembraneAuthor: Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia, Xiang-hong Sun
https://pubs.acs.org/doi/10.1021/acsami.9b00152
The goal of this study was to develop bioadhesive food protein nanoparticles using zein (Z), a hydrophobic corn protein, as the core and whey protein (WP) as the shell for oral pediatric drug delivery applications. Lopinavir (LPV), an antiretroviral drug, and fenretinide, an investigational anticancer agent, were used as model drugs in the study.Author: Saiful Islam, Joshua Reineke, Radhey Kaushik, Tofuko Woyengo, Aravind Baride, Mohammed S. Alqahtani,...
http://ijpsr.com/bft-article/protein-nanoparticles-future-of-drug-delivery-systems/?view=fulltext
CONCLUSION: The above discussed literature postulates that the protein nanoparticles are the future of drug delivery systems adhering to the basics of delivering therapeutics with efficacy, optimum bioavailability, minimizing side effects, target oriented and time release fundamentals (tables 2 and 3). Therefore, in near future, drug delivery ...
https://www.sciencedirect.com/science/article/pii/S0141813018337061
Being a natural component of milk as well as a natural carrier of bioactive agents, casein nanoparticles are highly promising as an effective yet non-toxic drug delivery agent. The next step of the work will be to carry out in vivo studies using these drug-loaded casein nanoparticles.Author: Sona Gandhi, Indrajit Roy
https://www.hindawi.com/journals/bmri/2014/180549/
Nanoparticles have increasingly been used for a variety of applications, most notably for the delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery systems have been developed for cancer treatment and various materials have been explored as drug delivery agents to improve the therapeutic efficacy and safety of anticancer drugs. Natural biomolecules such as ...Author: Warangkana Lohcharoenkal, Liying Wang, Yi Charlie Chen, Yon Rojanasakul
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