We have collected information about Protein Drugs Delivery for you. Follow the links to find out details on Protein Drugs Delivery.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/protein-drug-delivery
Formulation of protein and peptide drugs, their route of administration, rate, and overall pharmacokinetic profile in the body are pivotal factors in deciding the success of protein drug delivery. Until the 1950s, the oral route of drug delivery was the most preferred, …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
While the peptide and protein therapeutic market has developed significantly in the past decades, delivery has limited their use. Although oral delivery is preferred, most are currently delivered intravenously or subcutaneously due to degradation and limited absorption in the gastrointestinal tract.Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim
http://www.pharmtech.com/considering-protein-and-peptide-delivery
Jan 02, 2019 · Drug delivery challenges posed by protein and peptide therapeutics are many. Not only are the molecules large in size but they are hydrophilic, cannot easily cross biological barriers, are degraded by enzymes, rapidly leave the circulation system, and are highly charged, all of which complicate the delivery …
http://rjptonline.org/AbstractView.aspx?PID=2019-12-3-69
The present review briefly describes the possible methods for the delivery of protein and peptide drugs through various routes. KEYWORDS: Protein, Peptide, Drug delivery, Liposomes, Microparticles, Buccal delivery. Cite: L. Srinivas, V. Manikanta, M. Jaswitha. Protein and Peptide Drug Delivery - …Author: L. Srinivas, V. Manikanta, M. Jaswitha
https://www.sciencedirect.com/science/article/pii/B9780128179093000169
Various protein/peptide drug delivery systems have been extensively investigated to overcome the problems associated with the exogenous administration of protein and peptide therapeutics. In this chapter, different approaches for the delivery of proteins and peptides are discussed including chemical modifications, absorption enhancers, carrier systems, and various other approaches.Author: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade
https://link.springer.com/content/pdf/10.1208%2Fs12249-019-1325-z.pdf
protein polypeptide drug. BARRIERS TO ORAL DELIVERY OF PROTEIN AND PEPTIDE DRUG NPS Most of the protein and peptide drugs are macromolec-ular hydrophilic, in the extreme environment of gastrointes-tinal stability, susceptible to gastric acid and pepsin degradation; at the same time, because of its hydrophilicity,Author: Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia, Xiang-hong Sun
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