Adenoviral Delivery

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Adenovirus: The First Effective In Vivo Gene Delivery Vector

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900005/
    Jan 01, 2014 · Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge. Infect. Immun. 77 , 1561–1568 [ PMC free article ] [ PubMed ]Author: Ronald G. Crystal

Adenoviral Gene Delivery for Mammalian Expression—Getting ...

    https://www.thermofisher.com/us/en/home/technical-resources/technical-reference-library/protein-expression-support-center/adenoviral-gene-delivery-support/adenoviral-gene-delivery-support-getting-started.html
    Find answers to commonly asked questions related to adenoviral gene delivery for mammalian expression, ranging from setting up of the experiment to biosafety features, cloning, adenovirus production, storage and amplification of adenoviral stocks, viral titering, transduction, and analysis of …

Direct delivery of adenoviral CRISPR/Cas9 vector into the ...

    https://www.pnas.org/content/116/27/13288
    Jul 02, 2019 · Considering these characteristics of adenovirus-mediated gene delivery, the adenoviral vector may be a more desirable delivery system that prevents potential off-target mutations because of temporary expression of gRNA and Cas9.Author: Joonbum Lee, Jisi Ma, Kichoon Lee

Adenoviruses as Gene-Delivery Vehicles NEJM

    https://www.nejm.org/doi/full/10.1056/NEJM199605023341809
    For gene therapy to realize its clinical potential, there must be efficient and safe strategies of delivering therapeutic genes to somatic cells in vivo. Perhaps this problem simply represents a sp...Author: James M. Wilson

Adenovirus Vector - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/medicine-and-dentistry/adenovirus-vector
    Adenoviruses are a suitable delivery system for gene therapy approaches for allergic disorders, if the strategy chosen requires high level but short-term transgene expression by the target cell, and if an immune response directed against the adenovector or its infected target cell is …

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